Insulin resistance is defined as the impaired sensitivity of tissues, mainly skeletal muscle, liver, and adipose tissues, to the action of insulin. Insulin resistance precedes 尾-cell dysfunction and plays a key role in the development of type 2 diabetes. After carbohydrate ingestion, insulin ...
Finally, the relationship between insulin resistance, steatosis and diabetes in NAFLD and HCV infection will be commented, along with the directions for future studies.A. LonardoP. LoriaLonardo A, Loria P. Insulin resistance, type 2 diabetes and chronic liver disease. A deadly trio. Clinical ...
Type II diabetes, also called non-insulin-dependent diabetes mellitus (NIDDM), is characterized by high blood glucose resulting from the genetic defect of the GLUT4 genome. The latter is manifested in the diminished glucose uptake into skeletal muscles. In normal human beings, insulin combines with...
Type 2 diabetes is a disease that affects how your child's body uses glucose (sugar). Type 2 diabetes develops because either the body cannot make enough insulin, or it cannot use the insulin correctly. You can help your child manage diabetes with healthy nutrition and physical activity ...
Insulin resistance is a core feature of type 2 diabetes mellitus (T2DM) and contributes not only to the hyperglycaemia that defines diabetes mellitus but also to the hyperlipidaemia, inflammation, oxidative stress and atherosclerosis that accompany it T2DM substantially increases risk of not only cerebro...
The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat Rev Endocrinol. 2012; 8 (2):92–103. doi: 10.1038/nrendo.2011.138. [ Cross Ref ]Szendroedi J, Phielix E, Roden M. The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat Rev ...
Insulin Resistance and Type 2 DiabetesInsulin Resistance and Type 2 DiabetesFor well over half a century, the link between in-sulin resistance and type 2 diabetes has been recognized. Insulin resistance is important. Not only is it the most powerful predictor of future development of type 2 diab...
Type 2 diabetes occurs when your body's cells resist the normal effect of insulin, which is to drive glucose in the blood into the inside of the cells. This condition is called insulin resistance. As a result, glucose starts to build up in the blood....
Insulin resistance (IR) correlates with mitochondrial dysfunction, free fatty acids (FFAs), and intramyocellular lipid (IMCL) in adults with type 2 diabete... M Cree-Green,A Gupta,GV Coe,... - 《Journal of Diabetes & Its Complications》 被引量: 16发表: 2016年 Effects of rice bran oil...
Obesity and type 2 diabetes are the most frequent metabolic disorders, but their causes remain largely unclear. Insulin resistance, the common underlying abnormality, results from imbalance between energy intake and expenditure favouring nutrient-storage pathways, which evolved to maximize energy utilization...