Cancer stagingis the process of determining how muchcanceris within the body (tumor size) and if it has spread. Forbreast cancer, this might take the form of clinical (pre-surgical) staging or pathologic (surgical) staging. Breast cancer is classified by stages. There are five stages of bre...
Cancer stagingis the process of determining how muchcanceris within the body (tumor size) and if it has spread. Forbreast cancer, this might take the form of clinical (pre-surgical) staging or pathologic (surgical) staging. Breast cancer is classified by stages. There are five stages of bre...
The disclosure further comprises a method to determine therapeutic treatment of estrogene-receptor negative breast cancer patients, a method of determining the tumor grade of said cancer patients, said methods using expression profiling of the genes above.ERLANDER Mark G....
Breast cancer (BC) is the most frequently invasive malignancy and the leading cause of tumor-related mortality among women worldwide. Cancer metastasis is a complex, multistage process, which eventually causes tumor cells to colonize and grow at the metastatic site. Distant organ metastases are the...
Methods. We identified 123,780 cases of stages 1–3 primary female invasive breast cancer from California Cancer Registry. The surrogate classification was derived using ER/PR/HER2 and tumor grade. Kaplan-Meier survival analysis and Cox proportional hazards modeling were used to assess differences in...
Interestingly, GLO1 up-regulation correlates with advanced tumor grade (p<0.05). These findings demonstrate the association of GLO1 overexpression with tumor grade and pointed out for additional studies to establish the importance of GLO1 in breast cancer. 展开 ...
The present invention further comprises means for determining a method of treating estrogen receptor-negative breast cancer, the cancer patient to determine the level of the tumor, the method using the above-described gene expression profiles. 展开 ...
Borgquist S, Wirfält E, Jirström K et al (2007) Diet and body constitution in relation to subgroups of breast cancer defined by tumour grade, proliferation and key cell cycle regulators. Breast Cancer Res 9:R11. https://doi.org/10.1186/bcr1644 Article PubMed PubMed Central CAS Goog...
cluster 2 comparison, likely reflect both a general tumor-specific miRNA pattern, but also the aggressiveness of particular breast cancer subtypes. This observation came from the fact that samples in cluster 1 originated from more advanced tumors (high-grade, high immune score, hormone receptor-...
The internal heterogeneity of breast cancer, notably the tumor microenvironment (TME) consisting of malignant and non-malignant cells, has been extensively explored in recent years. The cells in this complex cellular ecosystem activate or suppress tumor