The number of patients with grade 1 tumors who developed distant metastasis or died without developing a second event of higher-grade tumor was limited (4%) [44]. This observation implies that grade 1 breast cancer studies that do not include pathology review and evaluation of the second event...
TUMOR-infiltrating immune cellsBREAST cancerBREAST cancer prognosisCANCER invasivenessCANCER patientsBackground: The histological grade is an important factor in the prognosis of invasive breast cancer and is vital to accurately identify the histological grade and reclassify of Grade2 st...
Differences in emotional distress between breast tumor patients with emotional inhibition and those with emotional expression The differences in affective status between patients who restrain their negative emotion and those who express negative emotion after being given their bre... I Yumi,S Kazutaka,A...
grade 1) have low dissemination potential in general, although less differentiated, more proliferative high grade tumors (e.g. grade 3) form metastases much more frequently. Low grade breast tumor cells spread predominantly via lymph vessels and lymph nodes are therefore the first site of tumor ce...
Are they very abnormal and look very different than the normal breast cells? We call that 'differentiation.' 'Well-differentiated' means they're close to normal breast cells. 'Poorly-differentiated' means that they are very different than normal breast cells and are therefore more malignant -- ...
1. Introduction Breast cancer is a heterogeneous disease with simultaneous perturbations in multiple genes or gene products [1], which serve the specific function inside or outside the cell through molecular interactions with their partners. Consequently, a particular cellular task (cell proliferation, ...
Using a bioinformatics approach, we analyzed the profiles of secreted tumor and normal interstitial fluid (IF) microRNAs, from women with breast cancer (BC). We carried out differential abundance analysis (DAA), to obtain miRNAs, which were enriched or depleted in IFs, from patients with differen...
For p53 and WT-1 immunohistochemistry, uniformly dis- tributed and strong nuclear staining in at least 50% of the tumor cells was considered a positive, although diffuse positivity was the norm. Similarly, immunopositivity for p16ink4 was scored positive when uniform and strong nuclear and ...
data support a role for the64 integrin in tumor cell migration and invasion, particularly in breast carcinoma cells, but clinical data on this potentially important integrin are limited. Thehas been shown to cluster with genes characteristic of basal/myoepithelial cells in cDNA microarray analyses ...
Objective To study the value of tumor vein detected by susceptibility weighted imaging(SWI) in evaluation of glioma grade. Methods Thirty-nine cases of gliomas were confirmed pathologically, including 18 cases of low-grade gliomas(WHOⅠ-Ⅱgrade) and 21 cases of high-grade gliomas(WHO Ⅲ - Ⅳ ...