Tumour size and vascular invasion predict distant metastasis in stage I breast cancer. Grade distinguishes early and late metastasisBackground: Recent Dutch guidelines recommend adjuvant systemic treatment (AST) for women with high grade stage I breast carcinoma ⩾1 cm. High grade is defined as ...
Extensive cancer-associated hypomethylation of juxtacentromeric satellite DNA and global DNA hypomethylation were common even in grade-1 or stage-1 carcinomas, which suggests that demethylation of the genome is an early event in breast carcinogenesis....
This paper reports a case of low-grade adenosquamous carcinoma (LGASC) arising in a 69-year-old woman, who presented with a 1-cm palpable mass on her right breast. Core needle biopsy diagnosed the mass as a fibroadenoma. After six months, the mass increased in size, and the patient rece...
Histological grading of 160 primary infiltrating breast carcinomas showed that both oestrogen and progesterone receptor status are strongly related to grade, tumours that are receptor positive tending to be of lower grade than the receptor negative. The nuclear factors used in grading were those that ...
Because high levels of DcR2 expression have recently been correlated with carcinogenesis in the prostate and lung, this study investigated the importance of TRAIL and TRAIL receptor expression in breast cancer patients with invasive ductal carcinoma, taking various prognostic markers into consideration....
展开 关键词: Cell Line, Tumor Humans Carcinoma, Ductal, Breast Breast Neoplasms Lactoylglutathione Lyase Peptide Fragments Proteome Electrophoresis, Gel, Two-Dimensional Tissue Array Analysis Case-Control Studies DOI: 10.3892/ijo.2012.1478 被引量: 55 年份...
Here, we present evidence that the routinely evaluable immunohistochemical MIB1/Ki67 labelling index (MIB-LI) can classify grade 2 tumours into two clinically distinct subgroups. In this study, growth fractions of 1,550 primary operable invasive breast carcinomas were immunohistochemically assayed on ...
The diagnostic value of these markers in distinguishing benign from malignant breast lesions has not been well examined. To evaluate the diagnostic value of CD44s in distinguishing between intraductal papillomas and papillary carcinomas of the breast, which may be difficult......
10-year survival in female breast cancer patients according to ER, PR and HER2 expression: a cancer registry population-based analysis Article 21 September 2022 Correlation of tumour subtype with long-term outcome in small breast carcinomas: a Swedish population-based retrospective cohort study ...
Given that NGS has been shown to provide prognostically relevant information for invasive ductal carcinomas of NST and lobular carcinomas, which together account for greater than 80% of all breast cancers, the systematic inclusion of histological type in breast cancer routine synoptic reports is ...