Cancer grading is part of breast cancer staging and is an indicator of the the aggressiveness of breast cancer. Breast cancer staging is not solely based on the grade of the tumor.Other factors include thesize and locationof the tumor, the number oflymph nodesaffected, and the degree ofmetast...
The disclosure further comprises a method to determine therapeutic treatment of estrogene-receptor negative breast cancer patients, a method of determining the tumor grade of said cancer patients, said methods using expression profiling of the genes above.ERLANDER Mark G....
Examination of Tumor Regression Grading Systems in Breast Cancer Patients Who Received Neoadjuvant TherapyBreast cancerGrading systemsNeoadjuvant therapyRegression patternResidual cancer burdenNeoadjuvant therapy is a common form of treatment in locally advanced breast cancer (LABC) patients. Besides some ...
Histological sections of the primary tumour from 496 women with operable breast cancer have been examined for purposes of histological grading by two observers working independently. Each found a similar distribution of grade through the series, and a virtually identical influence of grade on prognosis...
The current evidence indicates that grading has limited value in advanced or metastatic breast cancer (stages III and VI) and grading is not expected to change treatment decisions and therefore need not be considered in these cases. Grade and tumor type The prognostic value of histological grade ...
Naume B, Borgen E, Kvalheim G, Karesen R, Qvist H, Sauer T, Kumar T, Nesland JM (2001) Detection of isolated tumor cells in bone marrow in early-stage breast carcinoma patients: comparison with preoperative clinical parameters and primary tumor characteristics. Clin Cancer Res 7: 4122–41...
of malignancy (6-9) and mitotic rates as part of the grading system are difficult to assess in exact manner, we widened the grading system by evaluation of the proliferative compartment to get more information about proliferation activity as an important factor for tumor-progression (15, 16). ...
We consider the problem of assessing inter-rater agreement when there are missing data and a large number of raters. Previous studies have shown only 'moderate' agreement between pathologists in grading breast cancer tumour specimens. We analyse a large but incomplete data-set consisting of 24,177...
Grading breast cancer tissues using molecular portraits Mol. Cell. Proteomics, 12 (2013), pp. 3612-3623 Google Scholar [9] C.W. Elston, I.O. Ellis Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long...
The EMT inducer SNAIL1 regulates breast cancer metastasis and its expression in human primary breast tumor predicts for poor outcomes. During tumor progression SNAIL1 has multiple effects in tumor cells that can impact metastasis. An inflammatory tumor m