Molecular and cell biology of brain tumor stem cells: lessons from neural progenitor/stem cells. Neurosurg Focus. 2008; 24 :E25. doi: 10.3171/FOC/2008/24/3-4/E24. [ Cross Ref ]Xie, Z. and Chin, L. S. (2008). Molecular and cell biology of brain tumor stem cells: lessons from ...
Stem Cells and Prostate Cancer || is the existence of a stem cell with tumorigenic properties capable of regenerating all the differentiated cell types presented in the original tumor. The... Cramer,D Scott - Springer New York 被引量: 14发表: 2013年 Ovarian Stem Cell Biology and the Emergenc...
Tumor and stem cell biology transiently entrapped circulating tumor cells interact with neutrophils to facilitate lung metastasis development Cancer Res, 70 (14) (2010), pp. 6071-6082, 10.1158/0008-5472.CAN-09-4442 View in ScopusGoogle Scholar 79 T. Yoshimasu, T. Sakurai, S. Oura, et al....
[Stem cells and T- and B-lymphocytes in acute hypoxia] During the stepped rapid training of mice for hypoxia the number of colony-forming units in the blood and bone marrow increases and that in the spleen fall... BT Tulebekov,N Ash - 《Bulletin of Experimental Biology & Medicine》 被...
One of the best understood examples of this tumor cell biology is found in colorectal carcinoma cells. Colon cancer cells frequently express a mutated K-RAS protein, an autocrine-activated EGF receptor or a mutant B-RAF protein [1,2]. Downstream activation of the PI3K/AKT and ERK1/2 ...
3D spheroids provide a more physiologically representative model than traditional culture systems and can be used in many applications, including cancer research, drug screening, and stem cell research.3D tumor spheroids, also known as cancer spheroids, have been shown to mimic the...
Tumor-derived factors are thought to regulate thrombocytosis and erythrocytopenia in individuals with cancer; however, such factors have not yet been identified. Here we show that tumor cell-released kynurenine (Kyn) biases megakaryocytic–erythroid progenitor cell (MEP) differentiation into megakaryocytes...
In the last few decades, the role of cancer stem cells in initiating tumors, metastasis, invasion, and resistance to therapies has been recognized as a potential target for tumor therapy. Understanding the mechanisms by which CSCs contribute to cancer progression can help to provide novel therapeuti...
[54]. Treatment of cancer cells with conditioned media from macrophages and fibroblasts overexpressing miR-6794-5p confirmed that EMT, cell mobility, invasiveness, and stem cell ability increased in the presence of conditioned media from macrophages rather than that from fibroblasts (Fig. S8). These...
5b, c), supporting our experimental data that Dll1+ cells have stem-like properties that increase their invasive properties. NF-κB and Hypoxia signaling are intimately linked to chemoresistance through regulation of cell proliferation and survival in several cancers, including breast cancer37,38,39,...