Paving the road for lung stem cell biology: bronchioalveolar stem cells and other putative distal lung stem cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 293, L1092–L1098 (2007). Article CAS PubMed Google Scholar Rock, J. R. & Hogan, B. L. Epithelial progenitor cells in lung...
Journal2017,Seminars in Cell & Developmental Biology MengjiaQian, ...YunfengCheng 3.3Cancer stem cells Cancer stem cellsare defined as a kind of cells that have the specific ability to self-renew, reinitiate cancer, and reconstitute tumor cells[35]. It is the abilities of self-renewal and di...
Wnt signaling in stem and cancer stem cells [ J ]. Cur Opin... Peter Wend,Jane D. Holland,Ulrike Ziebold,... - 《Seminars in Cell & Developmental Biology》 被引量: 893发表: 2010年 microRNA Functions - Annual Review of Cell and Developmental Biology, 23(1):175 microRNAs (miRNAs) are...
Cancer stem cells (CSCs) show a remarkable sub class of cancer cells population which have a potential to organize and regulate stemness properties which possess a main particular responsibility for uncontrolled growth in carcinogenesis, production of different cancers in differentiated situation and also...
To cure cancer it is necessary to kill, differentiate or prevent the metastasis of cancer stem cells. Abstract Why are tumours heterogeneous, in terms of cell phenotype and proliferative potential, even in cases in which all cells are derived from a single clone? Ongoing mutagenesis can partially...
The development of cancer is a multistep process in which the DNA of a single cell accumulates mutations in genes that control essential cellular processes. Loss of cell–cell adhesion and cell polarity is commonly observed in advanced tumours and correlates well with their invasion into adjacent ...
These findings explained the unusual lack of BCR-ABL1 fusion in the B-ALL malignancies and also influenced decisions regarding maintenance imatinib after hematopoietic stem cell transplantation. By identifying common clonal variants or the evolution of subclonal variants, it was possible to distinguish ...
生物通报道,密歇根大学医学院内科学系分子医学与遗传学分部,细胞与发育生物学系,病理系的研究人员在最新一期的Cancer Cell发表p53与脑瘤研究进展,Expression of Mutant p53 Proteins Implicates a Lineage Relationship between Neural Stem Cells and Malignant Astroc
LGR5 marks resident adult epithelial stem cells at the gland base in the mouse pyloric stomach1, but the identity of the equivalent human stem cell population remains unknown owing to a lack of surface markers that facilitate its prospective isolation and validation. In mouse models of intestinal...
and Developmental Biology Department, Molecular, Cellular, University of California, Santa Barbara, CA, USA Denise J. Montell Contributions D.J.M. wrote the sections on Caenorhabditis elegans and Drosophila melanogaster. C.A.P and C.H.S. wrote the sections on Dictyostelium discoideum and zebrafish...