肺腺癌和肺鳞癌鉴别的初探 摘要目的:原发性支气管肺癌简称肺癌,为起源于支气管粘膜或腺体的恶 性肿瘤。肺癌发病率位居恶性肿瘤的首位,同时由于早期诊断不足致使预 后差。目前随着诊断水平提高、新化疗药物以及靶向治疗药物的出现,规 范有序的 君,已阅读到文档的结尾了呢~~...
Immunohistochemical analysis revealed a positive reaction for thyroid transcription factor-1 (TTF-1). Thus, we concluded that these were metastatic duodenal tumors from lung adenocarcinoma. Two courses of gemcitabine led to a complete remission in this duodenal metastasisand para-aortic lymph node ...
differentiationtumors(P<0.05),however,thepositiverateofKi67was46.51%,whichwassignificantlylowerthanthatofpatientswithmiddleandlowdifferentiationtumors(P<0.05).ThepositiveexpressionrateofKi67inpatientswithlymphnodemetastasiswassignificantlyhigherthanthatofpatientswithoutlymphnodemetastasis(P<0.05).Moreoverthepositiverate...
node metastasis and with moderate/high differentiated tumors;the one-year and two-year survival rates in19patients with cancerous TTF-1expression positive were84.2%and73.3%,both significantly higher than51.4%and35.1%(P<0.05)in 37patients with cancerous TIF-1negative;the one-year and two -...
Subsequent MSP analyses showed aberrant DNA methylation in TTF-1-negative thyroid carcinomas, but not in TTF-1-positive tumors. Concomitantly with DNA methylation, we demonstrated histone H3 modification is linked with transcriptional silencing of TTF-1. These findings suggest epigenetics is a key ...
The positive expression rates of TTF-1 and NapsinA in patients with high differentiation tumor were significantly higher than those of patients with moderate and low differentiation tumors(P<0.05),however,the positive rate of Ki-67 was 46.51%,which was significantly lower than that of patients ...
产品中文名称:ttf1(转录因子Nkx2 - 1)兔单克隆抗体,2044-1 产品英文名称:ttf1 (nkx2-1) rabbit monoclonal antibody, 2044-1 货号:pro_40114产地:epitomics 规格/价格:询价 产品详细说明: ttf1 (nkx2-1) antibody rabmab® cat.#: 2044-1
Specificity: This antibody reacts with TTF-1 protein found in adenocarcinomas of the lung and tumors originating in the thyroid. TTF-1 positive cells are found in Type II pneumocytes and Clara cells in the lung. In the thyroid, follicular and parafollicular ce...
Among patients with lung ade- nocarcinoma, those with TTF-1-positive cancer exhibit better prognosis than those with TTF1-negative cancer [4-6]. Using a transgenic lung cancer mouse model, deletion of TTF-1 has been shown to promote invasion and me- tastasis of lung adenocarcinoma, in ...
TTF-1-positive adenocarcinomas had statistically significant prevalence of female (p <0.01), nonsmoker (p <0.05), negative p53 staining (p <0.01), less frequent RB loss (p <0.05), and preserved expression of p27 (p <0.01). The results supported the TTF-1 lineage marker and suggested ...