The present invention provides a method of producing antibodies having the binding specificity of the reference antibody. Antibodies generated by the methods of the present invention has a minimal essential binding specificity determinant of at least one light chain CDR3 or heavy chain of the ...
Antibody specificity transfer using minimal essential binding determinantsThe present invention provides methods of making antibodies having the binding specificity of a reference antibody. Antibodies generated by the methods of the inventions have at least one minimal essential binding specificity determinant ...
In addition, inhibition studies using other monoclonal antibodies directed against the same antigen may help to delineate the epitope specificity of antibodies. 展开 关键词: Électrophorèse Anticorps monoclonaux Nitrate de cellulose Transfert Méthode ...
Furthermore, co-immunoprecipitation of apoB was also demonstrated by Western blot analysis of proteins immunoprecipitated with anti-MTP antibodies. In the same year Patel and Grundy transfected COS cells with various C-terminally truncated apoB polypeptides with MTP, immunoprecipitated apoB with anti-...
and 0.007 (3832).e, Mitochondria transfer between astrocytes (mitoDsRed+and GFAP+) and human GBM cells (GFP+) in vivo. Confocal microscopy of a GFP+P3 xenograft tumor immunostained with antibodies to GFAP (white color) was used to visualize astrocytes. Images are representative of at least ...
Because the FcRn randomly binds the Fc-region of IgG, one would predict that antigenic-specificity would not influence efficacy of transplacental transport and CMR would be similar for all antigens. However, such is not the case. For example, both HIgG (concentration) and PM (infection) have...
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Considering that the girl had a positivity to birch (>100 kU/L), apple, cherry and peach, which belong to the Rosaceae family, it is important to investigate the presence of IgE antibodies to Bet v 1 and nsLTP to evaluate the risk for serious systemic reactions. ...
The primary goals of the T cell section of the First International Workshop on Leucocyte Differentiation Antigens were to compare the reactivity of the reagents submitted to the Workshop, to identify antibodies of similar specificity, an... JA Hansen,PJ Martin,PG Beatty,... - Springer Berlin ...
Protection againstPseudomonas aeruginosainfection by passive transfer of anti-flagellar serum The specificity of adsorbed flagellar antisera for H-antigen was demonstratedin vitroby cross-agglutination assays, motility inhibition, and an ELISA. The specific flagellar antibody was determined to be an IgG. ...