, and/or clinical signs (e.g. jaundice) of a haemolytic transfusion reaction (HTR)? Are one, two, or all three of these criteria needed to make an antibody significant? For instance, is a shortened RBC survival with no obvious laboratory abnormalities and/or or clinical signs really ...
Increased detection of clinically significant antibodies and decreased incidence of delayed haemolytic transfusion reaction with the indirect antiglobulin ... BLOOD TRANSFUSION . 2011Okutsu M, Ohto H, Yasuda H, et al. Increased detection of clinically significant antibodies and decreased incidence of ...
Clinically significantNaturally occurring anti-M antibodies are mostly of the IgM class, however, an IgG component can also be present along with IgM. The IgM anti-M antibodies can be ignored if they are not reactive at 37掳C, but the patient should receive M antigen-negative red blood ...
Transfusion medicine in a developing country - alloantibodies to red blood cells in multi-transfused patients in Saudi Arabia. Multiple transfusions are frequently complicated by alloimmunization. This retrospective study aims to determine whether alloimmunization could be accounte... AGMA Gader,AKA Gh...
The association of biologically active lipids with the development of transfusion-related acute lung injury: a retrospective study. None of the donors had significant titers of HLA or HLA-DR antibodies; however, 50 percent had weak positivity for granulocyte antibodies. CONCLUSION: ... CC Silliman,...
Of the 97 AUS specimens that were treated with ficin, we were able to identify 25 new alloantibodies that would have otherwise been missed without ficin treatment. Thus, we believe our protocol enhances transfusion safety, while minimizing additional workload and cost. 展开 ...
p-value < 0.05 at a 95% confidence interval was considered statistically significant. In this study, a total of 883(883 for HBV and 366 for HCV) study participants were included. The overall prevalence of HBsAg and anti-HCV were 124/883(14%) and 73/366 (19.9%), respectively. The...
Adverse reactions requiring interruption or discontinuation of trastuzumab product treatment include CHF, significant decline in left ventricular cardiac function, severe infusion reactions, and pulmonary toxicity [see Dosage and Administration (2.3)]. In the metastatic gastric cancer setting, the most ...
The functional annotation of the significant genes found that upregulated genes were enriched in the regulation of the immune response, cell aggregation and activation, and innate immunity (eFigure 4A in the Supplement). The downregulated genes were enriched in metabolic processes (eFigure 4C in ...
N.S., not significant; ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001. Discussion For successful clinical application of hiPSC technology to platelet transfusion, it will be necessary to produce very large quantities of platelets. To achieve this goal, we will need to boost production ...