ShuttlefortransferofacetylgroupsfrommitochondriatothecytosolAcetyl-CoA is produced in mitochondria through the metabolism of fatty acids and the oxidation of pyruvate to acetyl-CoA. When ATP is needed, this acetyl-CoA can enter the Krebs cycle to drive oxidative phosphorylation. When ATP supplies are...
In E. coli [17], this is achieved with the help of the AMP-forming acetyl-CoA synthase. A homolog of this enzyme is found in P. bivia (Supplementary Table S1). P. bivia did not grow in the medium prepared with N2 instead of CO2 (Figure 2). This indicates that glucose utilization ...