Discusses regulatory elements that enable a cell to turn transcription of each gene on and off as needed. Resemblance of promoters to so-called dimmers; How promoters regulate gene expression; Predicting which transcri...
29, No. 1 © 2001 Oxford University Press DBTBS: a database of Bacillus subtilis promoters and transcription factors Takahiro Ishii, Ken-ichi Yoshida 1 , Goro Terai 2,3 , Yasutaro Fujita 1 and Kenta Nakai 3, * PharmaDesign, Tokyo 104-0032, Japan, 1 Department of Biotechnology, Faculty...
General Transcription Factors and Promoters Zachary F. Burton, in Evolution Since Coding, 2018 Abstract The last universal common ancestor (LUCA) promoters and general transcription factors evolved via iteration of a small number of simple DNA sequences and interacting protein motifs. Divergence of arch...
3.2.1 Transcription factors CCCTC-binding factor (CTCF) is a ubiquitously expressed 11-zinc finger protein that binds to the hTERT proximal exonic region (Renaud et al., 2005) and is thought to be the only factor that can negatively regulate the transcription of hTERT irrespective of cell ...
To test whether active loop extrusion is essential for maintaining various types of chromatin loops and transcription, we endogenously and homozygously tagged each of the three primary loop extrusion factors (CTCF, RAD21 or WAPL) with an auxin-inducible degron (AID) by clustered regularly repeating...
Many transcription factors regulate gene expression in a lineage- and process-specific manner, despite being expressed in several cell types. Here, the authors show that the Hox transcription factor Ubx has lineage-specific interactomes, which contribute to its cell context-dependent functions. Julie ...
(2012). Ethylene-responsive transcription factors interact with promoters of ADH and PDC involved in persimmon ( Diospyros kaki ) fruit de-astringency. J... T Min,X Yin,Y Shi,... 被引量: 5发表: 2015年 Ethylene-responsive transcription factors interact with promoters of ADH and PDC involved...
WOX11/12 function genetically upstream of WOX5/7, and the WOX11/12 proteins directly bind to the promoters of WOX5/7 to activate their transcription. Mutations in WOX5/7 result in defective primordium formation. Overall, our data indicate that the expression switch from WOX11/12 to WOX5/7...
Using both techniques, we screened for regulatory regions that become ectopically active during Ras-dependent oncogenesis, and identified 3778 regions that become (over-)activated during tumor development. Next, we applied motif discovery to search for candidate transcription factors that could bind ...
Transcription factors (TFs) regulate the gene expression of their target genes by binding to the regulatory sequences of target genes (e.g., promoters and enhancers). To fully understand gene regulatory mechanisms, it is crucial to decipher the relationships between TFs and DNA sequences. Moreove...