By studying Lola-I, a Drosophila zinc finger transcription factor, we show here that the promoter state can also be subject to developmental regulation independently of gene activation. Lola-I is ubiquitously expressed at the end of embryogenesis and causes its target promoters to become accessible ...
a TATA box. The RNA promoter, instead, has a sequence called an upstream control sequence (UCS) that is recognized by a protein called upstream binding factor (UBF). After they are bound, a larger protein complex, called transcription initiation factor-IB (TIF-IB). TIF-IB consists of the...
An RNA promoter is a sequence of nucleotides preceding a gene that encodes ribonucleic acid. The way that a RNA promoter...
The thyroid transcription factor TTF-2 is a forkhead-containing protein involved in thyroid-specific gene expression and necessary for thyroid morphogenesis. In this paper, we demonstrate that TTF-2 is able to inhibit the activity of the thyroid-specific transcription factors TTF-1 and Pax-8 only...
PURPOSE: A promoter or transcription factor of a gene which is specifically expressed in a flower is provided to artificially control expression time of a specific gene.;CONSTITUTION: A composition for specifically expressing a gene in a flower which is before or after pollination of rice plant ...
Although stromal fibroblasts play a critical role in cancer progression, their identities remain unclear as they exhibit high heterogeneity and plasticity. Here, a master transcription factor (mTF) constructing core-regulatory circuitry, PRRX1, which det
motility (Sakuma, et al.,2012) (Fig.4). Interestingly, it was demonstrated that in hormone-sensitive prostate cancer cells, androgens control ST3GAL2 transcription by inducing promoter demethylation, increasing GD1a expression, a sialoganglioside associated with tumor progression (Hatano, et al.,...
a heterodimeric protein responsible for forming the 7-methyl-guanosine(5')triphospho(5')nucleoside [m7G(5')ppp(5')N-] structure at the 5' end of mRNAs, as had been reported using a template with another intermediate promoter [Vos, J. C., Sasker, M. & Stunnenberg, H. G. (1991) ...
Computational prediction of the high-quality and matrix-based transcription factor binding site profiles in the proximal region of the SCN5A promoter (2000 nt upstream) based on JASPAR database (JASPAR2020, http://jaspar.genereg.net/), in which includes seven highly conserved binding sites of ...
ABSCISIC ACID-RESPONSIVE ELEMENT BINDING PROTEIN1 (AREB1) (i.e., ABF2) is a basic domain/leucine zipper transcription factor that binds to the abscisic acid (ABA)-responsive element (ABRE) motif in the promoter region of ABA-inducible genes. Here, we show that expression of the intact ARE...