(2006) Transcription factor activating enhancer-binding protein-2β: a negative regulator of adiponectin gene expression. J. Biol. Chem. 281, 31245-31253Ikeda K, Maegawa H, Ugi S, Tao Y, Nishio Y, Tsukada S, Maeda S, Kashiwagi A (2006) Transcription factor activating enhancer- binding ...
No existing method to characterize transcription factor (TF) binding to DNA allows genome-wide measurement of all TF-binding activity in cells. Here we present a massively parallel protein activity assay, active TF identification (ATI), that measures the DNA-binding activity of all TFs in cell ...
regulate neuronal disorders. Activation of AP1 transcription factor is an important signaling event activated by the LDAs. HNE-mediated cytotoxicity has been linked to enhanced AP1 nuclear binding activity in hepatic stellate cells, pancreatic cells, neuronal cells, fibroblasts, human hematopoietic ste...
Direct protein–protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans In the nematode Caenorhabditis elegans, the zinc finger transcriptional regulator TRA-1A directs XX somatic cells to adopt female fates. The mem...
Although repetitive DNAs are not typically considered as regulatory elements that directly affect transcription, they can contain binding sites for some transcription factors. Here, we demonstrate that binding of the transcription factor CCAAT/enhancer-binding protein alpha (C/EBPalpha) to the mouse ...
E. A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. Neuron 33, 383–395 (2002). CAS PubMed Google Scholar Burgoyne, R. D. & Weiss, J. L. The neuronal calcium sensor family of Ca2+-binding proteins. Biochem. J. 353, 1–12...
Trans-actingfactorsareproteinsthatbindtothecis-actingelementstocontrolgenetranscription.e.g.transcriptionfactor(TF),repressor,activator…与顺式作用元件结合，调控基因转录的蛋白质。如转录因子、阻遏蛋白、激活蛋白……cis-acting–AsitethataffectstheactivityonlyofsequencesonitsownmoleculeofDNA.trans-acting–Aproduct...
focusedonmembersofthemitogen-activatedprotein kinase(MAPK)familyandtheirdownstreamtarget,the transcriptionfactorAP-1. PRINCIPALFINDINGS 1.NOinducesapoptosisviaAP-1activation incardiomyocytes TotestwhetherNOactivatesthetranscriptionfactor AP-1incardiomyocytes,bindingactivityofAP-1in nuclearextractsfromthesecellswasanaly...
CCAAT binding transcription factor binds and regulates human COL1A1 promoter activity in human dermal fibroblasts: Demonstration of increased binding in sy... B Saitta,S Gaidarova,L Cicchillitti,... - 《Arthritis & Rheumatism》 被引量: 0发表: 2000年 Modulation of human α1(I) procollagen ...
Activating Transcription Factor 7 (AFT7) (C-Term) 抗体 公司简介 上海钰博生物科技有限公司是2012年5月由“海归”组成的创业团队与两个专业投资机构发起成立的,以开发生产科研试剂和特色检验产品为方向,经过两年多的努力,已经建立了免疫学和分子生物学的五个技术平台,开发了ELISA/ELISpot酶联免疫试剂盒、重组蛋白...