activating transcription factor (ATFA family of proteins containing homologous basic/leucine-zipper ( bZIP ) binding domains; it is regulated by the JNK signal transduction pathway. Mutations in ATF2 interfere with the retinoblastoma and E1A oncogene's transcription suppressing activities. ATF6 is a ...
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Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases. 1992. Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases...
G. The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis. Gene 273, 1–11 (2001). Article CAS PubMed Google Scholar Kim, E. Y. et al. ATF3 plays a ...
The solution conformations of two mutants of the ATF (activating transcription factor) binding site within the E2A promoter of adenovirus have been determined in vitro by NMR and CD methods. Both sequences have conformations which incorporate north-like sugar puckers in helices which are stacked in...
Activating transcription factor 4 (ATF4) belongs to the ATF/CREB (activating transcription factor/cyclic AMP response element binding protein) family of basic region-leucine zipper (bZip) transcription factors, which have the consensus binding site cAMP responsive element (CRE). ATF4 has numerous ...
Activating Transcription Factor-6 (ATF6) Mediates Apoptosis with Reduction of Myeloid Cell Leukemia Sequence 1 (Mcl-1) Protein via Induction of WW Domain Binding Protein 1 来自 掌桥科研 喜欢 0 阅读量: 71 作者:N Morishima,K Nakanishi,A Nakano ...
Activating transcription factor (ATF)/cAMP-response element (CRE)-binding (CREB) proteins induce the CRE-mediated gene transcription depending on the cAMP stimulation. cAMP-dependent signaling oscillates in a circadian manner, which in turn also sustains core oscillation machinery of the circadian clock...
Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain. 来自 万方 喜欢 0 阅读量: 12 作者:Li, X Y,Green, M R 展开 摘要: ATF-2 is a cellular basic region-leucine zipper (bZIP) transcription factor that can mediate diverse transcriptional responses, ...
The endoribonuclease domain of active IRE1 cleaves the intron out of XBP1 (X-box binding protein 1) mRNA, the exons are joined to form the spliced mRNA, which is then translated into active XBP1 protein [66]. The transcription factor XBP1 binds directly to the ERSE (endoplasmic reticulum ...