TP53-Binding Protein 1 (53BP1) 来源宿主 兔 反应性 人 保存建议 建议收到该TP53-Binding Protein 1 (53BP1) Antibody产品后,储存温度为-20°C。避免重复冻融 其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提...
891 TP53 binding protein-1 and mutated in Ataxia-Telangiectasia gene variants affect TP53 mutations in lung cancerEUROPEAN JOURNAL OF CANCER -SUPPLEMENT-ZienolddinyS.SkaugV.HaugenA.
Identified as a TP53-binding protein, 53BP1 is a key regulator of the cellular response to double-strand breaks, a TP53-independent activity. Recent data have established a new TP53-dependent function for 53BP1 in mitotic surveillance after centrosome loss.Access through your organization Check ac...
并计算出总的携带rs7519753 “C”等位基因患者在接受聚乙二醇干扰素后的治愈率是非携带者的2.3倍。在机制探究上，作者发现，该SNP位于TP53BP2(tumor protein 53 binding protein 2)基因启动子上游18kb处，所在序列并无任何的已知功能。但多个与之有着显著连锁不平衡(即总是一块儿出现)的SNP则位于预期调控TP53BP2...
同时,TP53和TP73序列中间均含有DNA结合域(DNA binding domain,DBD)。另外,在TP73的3’端含有不育α基序域(sterile alpha motif domain,SAM),在肿瘤细胞基因组中该区域通常缺失[5]。TP73基因,可以转录出35个mRNA转录本,理论上能翻译产生29种p73蛋白质亚型。目前...
IF 1:10 - 1:100 Western blot analysis of extracts of various cell lines, using TP53 antibody. Immunofluorescence analysis of HeLa cells using TP53 antibody. Background: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The en...
where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasio...
别名BCC7; LFS1; P53; TRP53 相关类别一抗储存冷冻(-20℃) 避光 宿主Mouse反应种属Human , Monkey , Mouse 克隆类型mouse monoclonal抗原TP53 编 号包装库存目录价(￥)您的价格(￥)数量 D199442-0100100 ul预计5日内发货20002000 产品描述 概述 This gene encodes a tumor suppressor protein containing transcrip...
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes ...
指标别名 Antigen NY CO 13;Cellular tumor antigen p53;LFS1;P53;Phosphoprotein p53;TP53;TRP53;tumor protein p53;Tumor suppressor p53 克隆性 Monoclonal 检验物种 human 应用范围 WB,IHC,IF,FCM 基因名称 TP53 克隆号 OTI3D5 抗体来源 Mouse 抗体类型 IgG1 免疫原 Full length human recombinant protein of...