Tom复合体,即TOM complex,是细胞中负责蛋白质转运的一个复合物。它是细胞质同分泌途径中一个重要的功能模块,参与蛋白质的合成、转运和定位等多个生物学过程。本文将从Tom复合体的组成、功能以及与其他细胞器之间的相互作用等方面进行深入探讨。 一、Tom复合体的组成 Tom复合体由多个亚基组成,包括Tom20、Tom22、Tom...
The TIM/TOM complex (mitochondrial protein-transporting ATPase) is a protein complex that translocates proteins and some non-coding RNA (ncRNA) into and out of mitochondria (Bömer et al., 1997). From:Mitochondrion,2022 About this page
A further outer membrane protein, Mim1, plays a less defined role in assembly of Tom40 into the TOM complex. The three receptors Tom20, Tom22, and Tom70 are anchored in the outer membrane by a single transmembrane 伪-helix, located at the N terminus in the case of Tom20 and Tom70 ...
6月22日,清华大学生命科学学院隋森芳教授课题组在《美国科学院院报》(Proc Natl Acad Sci U S A)期刊上发表了题为“Tom20和Tom22的胞质结构域作为人源线粒体TOM复合体受体的结构基础”(Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors)的研究论文。通过冷冻电镜单颗...
Thekey difference between TIM and TOM complexis that TIM (translocase of the inner membrane) complex is a complex of proteins found in the inner mitochondrial membrane ofmitochondriawhile TOM (translocase of the outer membrane) complex is a complex of proteins found in the outer mitochondrial membr...
2022年6月22日，清华大学结构生物学高精尖创新中心隋森芳教授课题组在《美国科学院院报》（Proc Natl Acad Sci U S A）杂志上发表了题为：“Tom20和Tom22的胞质结构域作为人源线粒体TOM复合体受体的结构基础（Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors）” 的...
Fig. 4: Structure of the tetrameric TOM complex. Full size image Discussion Fig. 5: Model of preproteins import through TOM complex. The preproteins are recognized and guided to the Tom40 pores by Tom20, Tom70, and Tom22, where the electrostatics of the complex further distinguish different...
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三沙颈岬 complex tombolo[地质] 复合连岛沙洲 ; 复连岛沙洲 ; 复复成陆系岛 tombolo island[地理] 陆连岛 double tombolo 陆系岛 ; 双连岛沙坝 combined tombolo 结合沙颈岬 tombolo cluster[地理] 连岛沙洲群 single tombolo 单沙颈岬单连河洲 raised tombolo 上升连岛沙洲 tombolo series 连岛沙洲群 ...