Tom复合体,即TOM complex,是细胞中负责蛋白质转运的一个复合物。它是细胞质同分泌途径中一个重要的功能模块,参与蛋白质的合成、转运和定位等多个生物学过程。本文将从Tom复合体的组成、功能以及与其他细胞器之间的相互作用等方面进行深入探讨。 一、Tom复合体的组成 Tom复合体由多个亚基组成,包括Tom20、Tom22、Tom...
Fig. 4: Structure of the tetrameric TOM complex. Full size image Discussion Fig. 5: Model of preproteins import through TOM complex. The preproteins are recognized and guided to the Tom40 pores by Tom20, Tom70, and Tom22, where the electrostatics of the complex further distinguish different...
6月22日,清华大学生命科学学院隋森芳教授课题组在《美国科学院院报》(Proc Natl Acad Sci U S A)期刊上发表了题为“Tom20和Tom22的胞质结构域作为人源线粒体TOM复合体受体的结构基础”(Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors)的研究论文。通过冷冻电镜单颗...
因为根据 Complex 的说法,Nike 目前已表态:「我们目前不与 Tom Sachs 的工作室合作,也没有计划发布新鞋。」 Tom Sachs x NikeCraft Mars Yard 2.0 虽然人们仍然认为 Tom Sachs 和 Nike 正在开发第三款 Mars Yard 运动鞋,但 Nike 似乎没有打算发布该鞋款,至少短期内不会。 不过Nike 也并没有明确表示与 Tom...
It is postulated that the transport may be supported by the protein import machinery of the outer membrane, the TOM complex (translocase of the outer membrane). We demonstrate here that in the absence of functional porin1, the blockage of the TOM complex by the fusion protein termed pb 2-...
1.用来划分音节.2.手写的时候,当一行的末尾无法写完一个单词的时候,需要把一个单词拆成两个部分,前半部分写在该行的末尾,后半部分写在新的一行的开头.从哪里拆呢?从你看到的任意一个圆点的地方拆成两个部分.当然,还有一些例外.你如果系统地学大学英语写作会学这些的.
2022年6月22日，清华大学结构生物学高精尖创新中心隋森芳教授课题组在《美国科学院院报》（Proc Natl Acad Sci U S A）杂志上发表了题为：“Tom20和Tom22的胞质结构域作为人源线粒体TOM复合体受体的结构基础（Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors）” 的...
Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM22·54 complex Members of the mitochondrial carrier family such as the ADP/ATP carrier (AAC) are composed of three structurally related modules. Here we show that each of... Maxi,Endres,Walter,... - 《Embo ...
OMM proteins containing one transmembrane segment presumably insert at the interface of the Tom40 dimer of the TOM complex. OMM, outer mitochondrial membrane; IMM, inner mitochondrial membrane; IMS, intermembrane space; SAM, sorting and assembly machinery; TIM, translocase of the inner mitochondrial ...
The TOM complex in the OM functions as a protein entry gate through which over 90% of the mitochondrial proteome is imported. The TOM complex consists of the channel-forming β-barrel protein Tom40 and six α-helical membrane proteins; these include the receptors Tom20, Tom22, and Tom70 ...