Of particular interest are recent discoveries showing that the TOM core complex can act as a mechanosensor, where the pores close as a result of interaction with membrane-proximal structures. We highlight unusual and new correlations between the structural elements of the TOM complexes and their ...
The translocase of the outer mitochondrial membrane (TOM) complex is the main entry gate for mitochondrial precursor proteins synthesized on cytosolic ribosomes. Here we report the single-particle cryo-electron microscopy (cryo-EM) structure of the dimer
Looking for the right commercial property to buy or lease for your growing business? Have you heard there's money to be made in commercial and investment real estate, but just don't know how to get started? The world of commercial and investment real estate can be complex and confusing. ...
Trees simplify complex models allowing systems engineers and stakeholders to quickly grasp the relationships between model elements within the hierarchy. A system model visualized as a tree diagram. Nested Structure A nested structure groups related model elements, helping systems engineers and stakeholders...
The TOM complex is the main entry gate for protein precursors from the cytosol into mitochondria. We have determined the structure of the TOM core complex by cryoelectron microscopy (cryo-EM). The complex is a 148 kDa symmetrical dimer of ten membrane protein subunits that create a shallow fun...
In autophagy, Myosin VI can facilitate the maturation of autophagosomes through interactions with Tom1 and the autophagy receptors, Optineurin, NDP52 and TAX1BP1. Here, we report the high-resolution crystal structure of the C-terminal cargo-binding domain (CBD) of Myosin VI in complex with Tom...
However, we did decide that, at least in theory it would have to be capable of selling everything complex and configurable from blinds to the evil flying monkeys envisioned in “Wizard of Oz”. We weren’t concerned. We baked parity-plus into the plan as well as into the psyche of our...
Define Tom Hawke. Tom Hawke synonyms, Tom Hawke pronunciation, Tom Hawke translation, English dictionary definition of Tom Hawke. n a container that has a rigid structure adj relating to a container that has a rigid structurerelating to a tough person Co
Commander complex regulates lysosomal function and is implicated in Parkinson’s disease risk Science Wednesday, April 9, 2025 Targeted MYC2 stabilization confers citrus Huanglongbing resistance Science Wednesday, April 9, 2025 2 views 0 comments ...
The YAML format is oriented towards configuration files just like TOML. For many purposes, however, YAML is an overly complex solution. TOML aims for simplicity, a goal which is not apparent in the YAML specification:http://www.yaml.org/spec/1.2/spec.html ...