人TNFRSF9位于染色体1p36。如图1所示，人TNFRSF9全长包含255个氨基酸（amino acid, aa），其中，17aa信号肽、169aa的胞外区、27aa跨膜区（p.187–213）和42aa的胞内区。大量研究发现，TNFRSF9是T细胞表面一种重要的激活型免疫检查点分子 [5, 6]。图1.TNFRSF9结构示意图*图片来源于Cancer gene therapy出版...
[5] Eckstrum, Kirsten, and Brent M. Bany. "Tumor necrosis factor receptor subfamily 9 (Tnfrsf9) gene is expressed in distinct cell populations in mouse uterus and conceptus during implantation period of pregnancy." Cell and tissue research 344.3 (2011): 567-576. [6] Cheuk, Adam TC, Gh...
基因序列:NCBI_Gene:500590 蛋白序列:UniProtKB:Q4V895 大鼠Rat Tnfrsf9 靶点分子功能(预测) Predicted to enable cytokine binding activity; identical protein binding activity; and signaling receptor activity. Predicted to be involved in regulation of cell population proliferation. Predicted to act upstream ...
提供的TNFRSF9人源重组蛋白(Q01)产品为带有GST标签的人源TNFRSF9部分序列重组蛋白,其对应的GeneID号为3604。 产品描述 与其它公司提供的重组蛋白不同,该TNFRSF9人源重组蛋白(Q01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并...
TNFRSF9 (4-1BB) cloned gene : ORF from ATG to Stop, in pUNO1 expression plasmid selectable in E.coli and mammalian cells. Fully sequenced.
Species Gene ID Accession Source Length MW Tag Human 3604 Q07011 E. coli 166aa 17.7kDa - About this Antibody Name Recombinant Human 4-1BB Receptor/TNFRSF9 (Recombinant Human 4-1BB Receptor; rHu4-1BB Receptor);重组人4-1BB受体/TNFRSF9 ...
详情介绍: 重组人类4-1BB受体/ TNFRSF9蛋白 SynonymsTNFRSF9, CD137 Antigen, T-cell Antigen ILA SpeciesHuman AccessionQ07011 GeneID3604 SourceEscherichia coli. Molecular Weight重组人类4-1BB受体/ TNFRSF9蛋白Approximately 17.7 kDa, a single non-glycosylated polypeptide chain containing 166 amino acids...
性状 Recombinant Human 4-1BBRTNFRSF9 是 TNF 受体超家族可诱导的T 细胞分子,能够促进抗原特异性T细胞的扩增,也能够阻止CD8+ T细胞的激活诱导死亡。 Synonyms rHu4-1BBR/TNFRSF9; CD137 ; 重组人源4-1BBR/TNFRSF9 Species Human Source E. coli Accession Q07011 Gene ID 3604 Molecular Weight Appr...
性状 Recombinant Human 4-1BBRTNFRSF9 是 TNF 受体超家族可诱导的T 细胞分子,能够促进抗原特异性T细胞的扩增,也能够阻止CD8+ T细胞的激活诱导死亡。 Synonyms rHu4-1BBR/TNFRSF9; CD137 ; 重组人源4-1BBR/TNFRSF9 Species Human Source E. coli Accession Q07011 Gene ID 3604 Molecular Weight Appr...
The goal of this study was to develop a strategy that allows candidate gene testing by allele-specific expression without prior knowledge of the credible causal variant.Tnfrsf9(encoding CD137) is a candidate gene for theIdd9.3type 1 diabetes (T1D) susceptibility locus in the nonobese diabetic ...