Signaling pathway via TNF-a/NF-kB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis. Am J Physiol Gastro- intest Liver Physiol 2009;296:G850-9.Onizawa M, Nagaishi T, Kanai T, et al. Signaling pathway via TNF-alpha/NF-kappaB in intestinal ...
Moreover, it has been recently reported that blockade of TNF receptor (TNFR) 1 signaling in infiltrating hematopoietic cells may prevent the development of colitis-associated cancer (CAC). However, it remains unclear whether the TNF-a signaling in epithelial cells is involved in the development of...
tnfr2激活nf-κb信号通路调控线粒体融合蛋白opa1在心力衰竭中的作用
39, No. 1, 121-127, February 2007 TNF-α upregulates PTEN via NF-κB signaling pathways in human leukemic cells Young-Rae Lee1, Hong-Nu Yu1, Eun-Mi Noh1, Hyun Jo Youn1, Eun-Kyung Song2, Myung-Kwan Han2, Chang-Sik Park3, Byung-Soo Kim4, Young-Seok Park4, Byung-Kwon Park4,...
关键词:黄连素;HepG2; 血管内皮细胞生长因子; 肿瘤坏死因子一a; 核转录因子一xB 中图分类号:R282.71 DOI:10.3870/j.issn.1672-0741.2014.04.004 EffectofBerberineonTNF-a·-inducedVEGFExpressionviaNF_。KBSignalingPathway LiJingbin,KeShandong,HuShaoming△ DepartmentofIntegratedTraditionalChineseandWesternMedicine,...
orthodontic tooth movement / periodontitis / rats / inflammatory response / tumor necrosis factor / NF-kB transcription factor / signaling pathway / gene ontology analysis 引用本文 导出引用 马遥, 姜兆伟 , 靳云轶 , 苗倩, 张春香 , 张淋坤. 大鼠牙周炎正畸牙移动初期TNF信号通路的基因本体分析[J]. ...
Sotetsuflavone suppresses invasion and metastasis in non-small-cell lung cancer A549 cells by reversing EMT via the TNF-α/NF-κB and PI3K/AKT signaling pathway Wang S, Yan Y, Cheng Z, Hu Y and Liu T. Sotet- suflavone suppresses invasion and metastasis in non-small-cell lung cancer A549...
although no visual signs of cellular toxicity were observed. However, when using the NF-κB inhibitor Ro, reported to inhibit NF-κB via selective inhibition of TNFα-induced IκBα [49], it decreased the TNFα-stimulated expression of mPGES-1 and COX-2 as well as the production of PGE2...
Within endothelial cells, TNFR2 promotes the survival of endothelial progenitor cells (EPCs) and endothelial cell (ECs) via the NF-κB signaling pathway while stimulating activation of the Etk/Bmx pathway to enhance VEGFR2 expression in ECs [64, 67, 68] (Fig. 3B). Upon interaction between ...
In this paper, we describe a phospholipid transmission pathway mediating tumor necrosis factor (TNF) activation of the nuclear transcription factor κB (NF-κB). Central to this TNF signaling route is the second messenger-like molecule ceramide, which is generated by sphingomyelin (SM) breakdown ...