(2009) Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis . Am J Physiol Gastrointest Liver Physiol 296 : G850–859Onizawa M, Nagaishi T, Kanai T, et al. Signaling pathway via TNF- alpha/NF-kappaB in ...
MIR-18a激活TNF介导的NF-kB信号通路。 Reference:MiR-18a-downregulated RORA inhibits the proliferation andtumorigenesis of glioma using the TNF-a-mediated NF-kB signalingpathway DOI:10.1016/j.ebiom.2020.102651 PMID:32062354
Further studies of the noncanonical NFkB pathway, for example, by studying functional polymorphisms in LTA or TNFSF11 (RANKL),22–24 could shed more light on any possible involvement of this pathway in anti-TNF therapy response. The TNF-a signaling pathway showed that a genetically determined ...
[关键词]肿瘤坏死因子;内皮细胞;丝裂原活化蛋白激酶;核因子一kB [中图分类号]R730.23 [文献标志码】A [文章编号]1672—2345(2010)06—0022—03 StudyontheRelationshipbetweentheMAPK andNF-kB PathwayinHUVEC InducedbyTNF-a WANGQing,LIUZhengxing,ZHAOYongming (TheDaliTeachingHospitalofDaliUniversity,Dali,...
OBJECTIVE: To identify the role of p38 MAPK- NF-kB signaling pathway in TNF-± induced IL-8 production in human hepatocellular carcinoma cells. METHODS: The concentrations of IL-8 from MHCC-97H cells were measured by an enzyme-linked immunosorbent assay (ELISA). The phosphorylation of p38 MAP...
Paeonol from Hippocampus kuda Bleeler suppressed the neuro-inflammatory responses in vitro via NF-κB and MAPK signaling pathway Inflammation has recently been implicated as a critical mechanism responsible for neurodegenerative diseases. In this study, paeonol (1-(2-hydroxy-4-methox... .W.A.,Hi...
In this paper, we describe a phospholipid transmission pathway mediating tumor necrosis factor (TNF) activation of the nuclear transcription factor κB (NF-κB). Central to this TNF signaling route is the second messenger-like molecule ceramide, which is generated by sphingomyelin (SM) breakdown ...
pathway)is signalingpathway andother numberof differentiation,apoptosispathophysiologicalprocess.Alarge studies have that tensionoverloadand demonstrated Inflammation,ventricular toactivationofthe over-activation JAK|STATafteracute system response pathway has been involvedin myocardialinflammatory.JAK/STATpathway ...
Resveratrol attenuates inflammation in the rat heart subjected to ischemia-reperfusion: Role of the TLR4/NF-κB signaling pathway. Mol. Med. Rep. 11, 1120–1126 (2015). CAS PubMed Google Scholar Al Humayed, S. et al. Suppression of acetaminophen-induced hepatocyte ultrastructural alterations ...
NF-kB在TNF-a誘導腎臟癌癌化機制角色之探討TheroleofNuclearFactor-kappaBinTNF-a-inducedtumorigenesisofrenalcellcarcinoma.許芝熒Chih-YingHsu醫學生物技術暨檢驗學系暨研究所關鍵詞:腎臟癌;腫瘤壞死因子;Keyword:TNF-a;NF-kB;RCC;摘要:Tumornecrosisfactor-α(TNF-α)主要為巨噬細胞所分泌之發炎性細胞激素,負責...