Thyroid hormone receptor-尾-selective agonist GC-24 spares skeletal muscle type I to II fiber shift[J] . Elen H. Miyabara,Marcelo S. Aoki,Antonio G. Soares,Rodrigo M. Saltao,Cassio M. Vilicev,Marisa Passarelli,Thomas S. Scanlan,Cecilia H. Gouveia,Anselmo S. Moriscot.Cell and Tissue ...
The preovulatory surge of luteinizing hormone reaches a maximum at 18.00 h on the day of pro-oestrus in female rats maintained with regular lighting from 0... CW Coen,MC Coombs - 《Neuroscience》 被引量: 122发表: 1983年 Epiquinamide: a poison that wasn't from a frog that was. In 200...
Thyroid hormones regulate cell growth, cell differentiation, and metabolic functions via interaction with the thyroid hormone nuclear receptors (TRs). Recently, a small class of halogen-free high-affinity thyroid hormone agonists has been developed that are highly selective for the TRbeta subtype. Beca...
Since systemic side effects of T3 may preclude its clinical use, and hepatocytes mostly express T3 hormone receptor beta (TRbeta), we investigated if selective TRbeta agonists like GC-1 may also have beta-catenin-dependent hepatocyte mitogenic effects. Here we studied the effect of GC-1 and ...
Thyroid hormone receptor(THR) ¥ 993 现货 规格 数量 2-Thiouracil 硫代由雪, Thiouracil, Deracil T1310141-90-2 2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM),是一种抗甲状腺化合物,可用作高度特异性的黑色素瘤探测物。
Thyroid hormone receptor(THR) ¥ 993 现货 规格 数量 2-Thiouracil 硫代由雪, Thiouracil, Deracil T1310141-90-2 2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM),是一种抗甲状腺化合物,可用作高度特异性的黑色素瘤探测物。
et al. Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α 1. Proc. Natl. Acad. Sci. USA 110, 16241–16246 (2013). 9. Venditti, P. et al. T3 and the thyroid hormone beta-receptor agonist GC-1 differentially affect metabolic...
From the structure, it became apparent that thyroid hormone is tightly packed inside the receptor molecule and that the last few amino acids of the receptor protein form an α-helix (helix 12), which acts as a kind of lid to close the box in which the hormone fits snugly. It has also...
(2003) Differential effects of triiodothyronine and the thyroid hormone receptor β-specific agonist GC-1 on thyroid hormone target genes in the brain. Endocrinology 144: 5480–5487 Google Scholar Roberts MR et al. (2006) Making the gradient: thyroid hormone regulates cone opsin expression in ...
Thyroid hormone receptor(THR) ¥ 993 现货 规格 数量 2-Thiouracil 硫代由雪, Thiouracil, Deracil T1310141-90-2 2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM),是一种抗甲状腺化合物,可用作高度特异性的黑色素瘤探测物。