The biochemical key to making this diagnosis is the persistence ofTSHsecretion despite definite overproduction ofthyroidhormones. The differential diagnoses arethyroid hormone resistance(seep. 400), drugs (amiodarone/amfetamine), and acute psychotic illness. Interference with one or other of thethyroid ...
Secondly, thyroid hormone analogues have the potential to suppress the hypothalamic–pituitary–thyroid axis, as exemplified by the retinoid X receptor agonist bexarotene [29], although this might be useful in certain forms of thyrotoxicosis [30]. Newer analogues, such as eprotirome, sobetiro...
In the preparation of a topical medicament for the treatment of dermatological impact state in the dermis, the present invention relates to the use of a thyroid hormone-like agonist compound or thyroid hormone at least one compound. The TR-β or TR-α, thyroid hormone-like agonist compound or...
E–J Changes in thyroid hormone levels among the three groups after intervention. E Free triiodothyronine (FT3), F free thyroxine (FT4), G thyrotropin (TSH), H triiodothyronine (T3), I thyroxine (T4), and J the T3/T4 ratio. K, L Changes in K thyroglobulin antibodies (TgAb) and L ...
thyroid-stimulating hormone receptor ttf-1: thyroid transcription factor-1 ttp: time to progression uicc: union for international cancer control ve-cadherin: vascular endothelial cadherin vegfr: vascular endothelial growth factor receptor vpa: valproic acid references siegel rl, miller kd, jemal a. ...
Eprotirome (KB2115) 是肝脏选择性甲状腺激素受体 (thyroid hormone receptor, TR) 激动剂。KB2115 对 TRβ 的亲和力略高于 TRα。Eprotirome 降低了低密度脂蛋白 (LDL) 胆固醇的浓度,可用于血脂异常和肥胖症的研究。- 高纯度,全球文献引用。
Triiodothyronine (T3) induces hepatocyte proliferation in rodents. Recent work has shown molecular mechanism for T3's mitogenic effect to be through activation of β-catenin signaling. Since systemic side effects of T3 may preclude its clinical use, and hepatocytes mostly express T3 hormone receptor ...
The liver is controlled by several metabolic hormones, including thyroid hormone, and characteristically displays high lysosomal activity as well as metabolic stress-triggered autophagy, which is stringently regulated by the levels of hormones and metabo
Skip to Main content Journals & Books Help Search My accountSign in Thyroid Hormone In subject area: Chemistry About this page
(TSI) • Peak in third to fourth decade; marked predominance in woman at least 5:1 • Strong association with HLA-DR3 and HLA-B8 • Clinically presents with thyrotoxicosis: muscle weakness, weight loss, exophthalmos, tachycardia, and goiter • Suppressed thyroid-stimulating hormone (TSH)...