Thus, Tg can be used as a tumor marker only after total thyroidectomy - apart from a few exceptions. In the case of a carcinoma of unknown origin and proven distant metastases which might be thyroid cancer, the level of serum Tg may be a useful indicator. A high Tg value suggests ...
Thyroid carcinomas are the most common malignant endocrine tumors. Thyroglobulin (Tg), a specific thyroid protein, is the most important tumor marker in thyroid oncology. After total thyroidectomy or radioiodine therapy, detectable or increasing serum Tg levels in patients with differentiated thyroid ...
Thyroglobulin is a normal protein produced by thyroid cells, both benign and malignant, and can be used as a tumor marker to detect residual thyroid cells in patients who have undergone thyroidectomy and 131I remnant ablation. AI generated definition based on: Medical Secrets (Fifth Edition), 201...
Assessment of the influence of thyroglobulin (Tg) autoantibodies and other interfering factors on the use of serum Tg as tumor marker in differentiated thyroid carcinoma. Thyroid. 1995;5:165–70. Article CAS PubMed Google Scholar Spencer CA. Recoveries cannot be used to authenticate thyroglobulin ...
phosphorylation and it is highly sensitivity to proteolysis. Acting as a substrate, Tg is used for the synthesis of thyroid hormones thyroxine (T4) and triiodothyronine (T3). Tg level can serve as a tumor marker of papillary and follicular thyroid cancer and elevated levels of anti-Tg antibodies...
Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves' disease.Organism species: Homo sapiens (Human) CATALOG NO. PRODUCT NAME APPLICATIONS Proteins RPA355Hu01 Recombinant ...
frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, and the ...
Given the cellular specificity of thyroglobulin, serum thyroglobulin is a very useful marker of persistent or recurrent tumor in patients after thyroidectomy and ablation of residual normal thyroid tissue. Approximately 60% of differentiated thyroid cancers take up enough iodide to be detected by ...
Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between ...
(iii) Since the reliability of Tg measured in the presence of TgAb is often uncertain, the TgAb trend (measured by the same method) may be a useful surrogate DTC tumor marker.Journal of Clinical Endocrinology & MetabolismPetrovic, IvanaLoPresti, JonathanFatemi, ShireenGianoukakis,...