A high Tg value suggests thyroid cancer; a value in normal range nearly excludes at least a well-differentiated carcinoma derived from follicular cells [18]. Furthermore, Spencer et al. [75] proposed the measur
processes, involving vesicles laden with thyroglobulin moving into and out of the cells, are somehow regulated so that under normal circumstances thyroglobulin neither accumulates in follicular cells nor are the lumens depleted. The physiological mechanisms for such traffic control are not yet understood....
Given the cellular specificity of thyroglobulin, serum thyroglobulin is a very useful marker of persistent or recurrent tumor in patients after thyroidectomy and ablation of residual normal thyroid tissue. Approximately 60% of differentiated thyroid cancers take up enough iodide to be detected by ...
range Levothyroxine therapy to achieve TSH goal of .–. mUI/L THS suppression therapy with levothyroxine to achieve subnormal serum TSH levels without thyrotoxicosis; Levothyr- oxine was withheld when thyroid functional remained within the reference range or when patients refused the ...
Therefore, it has been demonstrated that the immunoaffinity enrichment and LC-MS/MS assay performs well in comparison with an established immunoassay for Tg detection, even at the low picomolar range in human serum. This result is significant in that this level of detection has not been demonstrat...
24.Ahn, SH, Kim, WS. The effect of prophylactic central neck dissection during hemithyroidectomy on locoregional recurrence in patients with papillary thyroid carcinoma: a meta-analysis.Clin Exp Otorhinolaryngol2020;13:194–202.https://doi.org/10.21053/ceo.2019.01634.Search in Google ScholarPubMedPub...
normal range (0.5 to 0.9 mU/L) had a 3.7% prevalence of malignancy, patients with a slightly higher TSH (1 to 1.7 mU/L) had approximately a twofold increased risk of malignancy (8.3% prevalence), and patients with a serum TSH in the upper half of the reference range (1.8 to 5 mU/...
Given the cellular specificity of thyroglobulin, serum thyroglobulin is a very useful marker of persistent or recurrent tumor in patients after thyroidectomy and ablation of residual normal thyroid tissue. Approximately 60% of differentiated thyroid cancers take up enough iodide to be detected by ...