Chromatin is the physical representative of the epigenome. Histones are the main protein component of chromatin and form octamer cores, around which genomic DNA is wrapped. These nucleosomes are the regularly repeating units of chromatin, but they can vary from one genomic region to the other by...
Biophysics The structure of chromatin and its influence on gene regulation THE OHIO STATE UNIVERSITY Michael Poirier BernierMorgan WelshEukaryotic DNA is organized into a structural polymer called chromatin which ultimately controls important DNA processing functions such as transcription, DNA repair and DNA...
The structure of the ‘30 nm’ chromatin fibre has eluded us for 30 years and remains a major unsolved problem in biology. Progress during the past year has led to the proposal of two significantly different models: one derived from the crystal structure of a four-nucleosome core array ...
[Modification of the structure of chromatin and the nuclear matrix in pathological processes. Prospects for correction with drugs] Sjakste, N.I., Modification of the Structure of Chromatin and the Nuclear Matrix in Pathological Processes: Prospects for Correction with Drugs, Vopr. Med. Khim. , ...
Related to Chromatin structure:nucleosome chro·ma·tin (krō′mə-tĭn) n. A complex of nucleic acids and proteins, primarily histones, in the cell nucleus that stains readily with basic dyes and condenses to form chromosomes during cell division. ...
INTRODUCTIONAlleukaryoticchromosomesconsistsofaregularlyrepeatingprotein--DNAcomplexcalledthenucleosome(Kornberg,1977)[if.Itistraditionallyconsideredtobethefundamentalunitofchromatinstructure.Thephysicalpropertiesofnucleosomedependonsolutioncondition...关键词: Nucleosome core particle chicken erythrocytes atomic force microscopy...
Several levels of eukaryotic chromatin structure havebeen observed: the nucleosome, the 10 nm and 30 nm fibersand loop domains, apparently attached to the nuclearmatrix. In this research, the structure and function ofchromatin at two of these levels was investigated, withstudies on both nucleosome...
Internal structure of the chromatin subunit: The digestion of chromatin in situ with DNase I reveals, after denaturation, a regular series of single stranded DN
All the aspects of transcription are controlled by complexes that modify or remodel chromatin at the level of individual genes, gene clusters, or whole chromosomes. The MSL complex that is responsible for dosage compensation in Drosophila is an example of complexes that operate at the whole-chromoso...
Structures can occur in coding or non-coding RNAs, and learning more about RNA structure will improve our understanding of the transcriptome. Computational predictions of RNA structures have been important and continue to be refined and also combined with experimental methods. Experimental methods, which...