Radiotherapy is one of the main therapies for cancer. The process leading to radioresistance is still not fully understood. Cancer radiosensitivity is related to the DNA reparation of cancer cells and the tumor microenvironment (TME), which supports cancer cell survival. Factors that affect DNA repar...
This is particularly intriguing, as mevalonate pathway inhibitors, already used to treat hypercholesterolemia, are currently investigated as anti-cancer agents. In addition to preclinical data supporting the role of lipids in metastasis formation, studies using primary patient material also indicate that ...
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当当中国进口图书旗舰店在线销售正版《【预订】The Role of Bioactive Lipids in Cancer, Inflammation and Re... 9783030216368》。最新《【预订】The Role of Bioactive Lipids in Cancer, Inflammation and Re... 9783030216368》简介、书评、试读、价格、图片等相关信息
The changes are so prominent, that some lipids, such as phosphatidylserines, could even be considered as the cancer biomarkers. Additionally, some changes of biophysical properties of cell membranes lead to the higher resistance to chemotherapy, and finally to the disturbances in signalling pathways....
Cancer universally represents one of the largest public health concerns, substantially contributing to global disease burden and mortality. The multifaceted interplay of environmental and genetic factors in the disease aetiology and progression has requi
Lysosomes are an important component of the inner membrane system and participate in numerous cell biological processes, such as macromolecular degradation, antigen presentation, intracellular pathogen destruction, plasma membrane repair, exosome release
Lipids are essential constituents for malignant tumors, as they are absolutely required for tumor growth and dissemination. Provided by the tumor microenvironment (TME) or by cancer cells themselves through activation of de novo synthesis pathways, they
Lysosomes are an important component of the inner membrane system and participate in numerous cell biological processes, such as macromolecular degradation, antigen presentation, intracellular pathogen destruction, plasma membrane repair, exosome release
the synthesis and breakdown of these lipids, plays a key role in regulating the composition and functions of cells and cell membranes. An enzyme known as ELOVL6 elongates chains of fatty acids and is important in several cellular metabolic processes. However, the relationship...