Journal of Nutritional BiochemistryHubler MJ, Kennedy AJ. Role of lipids in the metabolism and activation of immune cells. J Nutr Biochem 2016;34:1-7.HUBLER MJ,KENNEDY AJ.Role of lipids in themetabolism and activation of immune cells[J].J NutrBiochem,2016,34:1-7....
Cancer cells need constant supplies of lipids to survive and grow. Lipid dependence has been observed in various types of cancer, including high-grade serous ovarian carcinomas (HGSOC), which is a lethal form ... Authors: Emilie Wong Chong, France-Hélène Joncas, Pierre Douville, Dimcho Bac...
The differences in lipid compositions between yeastlike cells and mycelium; the role of the structural and regulatory lipids, fatty acids, and their derivatives in morphological transformation of fungi; and the involvement of lipids in signal transduction and host-pathogen interactions are discussed. ...
interpreted as the protein interacting with the lipids in the monolayer and becoming embedded in it. Both ATG3 and the mutant were able to insert into these lipid monolayers extended at an initial surface pressure ≥23 mN/m (Fig.2B), i.e. above the maximum change in surface pressure caus...
ME Varney,WE Hardman,VE Sollars - 《Lipids in Health & Disease》 被引量: 36发表: 2009年 Granulocytic differentiation of myeloid progenitor cells by p130, the retinoblastoma tumor suppressor homologue. The retinoblastoma protein (pRB) and the related pocket proteins, p107 and p130, play crucial...
Cancer cells display sensitivity to ablation of fatty acid synthesis possibly as a result of diminished capacity to synthesize complex lipids involved in signaling or growth pathways. Evidence has accrued that phosphatidylcholine, the major phospholipid component of eukaryotic membranes, as well as choline...
In chronic obstructive pulmonary disease (COPD) apoptotic bronchial epithelial cells are increased, and their phagocytosis by alveolar macrophages (AM) is decreased alongside bacterial phagocytosis. Epithelial cellular lipids, including those exposed on
ofNB4cells into granulocytes which starts to be evident following 72–96 h [9]. Using a lipidomic approach [18], we determined the number and types of lipids observed in the two cell-lines. Principal-component-analysis (PCA) indicates thatNB4andNB4.306cells present with similar lipidomic ...
it has been shown that LDs are also present in mammal immune cells, such as neutrophils and macrophages, where they play important roles in inflammatory or infectious processes, increasing in number upon different types of immune challenges and thereby serving as reliable markers of immune cell acti...
Glycosphingolipids (GSLs) are amphipathic lipids ubiquitously expressed in all vertebrate cells and body fluids, but they are especially abundant in the nervous system. The synthesis of GSLs generally is initiated in the endoplasmic reticulum and completed in the Golgi apparatus, followed by ...