On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc. Natl Acad. Sci. USA 102, 18773–18784 (2005). This study proposes a direct recognition model for sensing ER stress in yeast. CAS PubMed PubMed Central Google Scholar Zhou, J. et al. The crystal structure ...
Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN Author links open overlay panelJulian Stingele 1, Roberto Bellelli 1, Ferdinand Alte 2, Graeme Hewitt 1, Grzegorz Sarek 1, Sarah L. Maslen 3, Susan E. Tsutakawa 4, Annabel Borg 1, Svend Kj...
Accurate chromosomal DNA replication is essential to maintain genomic stability. Genetic evidence suggests that certain repetitive sequences impair replication, yet the underlying mechanism is poorly defined. Replication could be directly inhibited by th
Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN Mol. Cell, 64 (2016), pp. 688-703 View PDFView articleGoogle Scholar Stingele et al., 2017 J. Stingele, R. Bellelli, S.J. Boulton Mechanisms of DNA-protein crosslink repair Nat. Rev. Mol...
Regulation of the genes from phenylpropanoid–flavonoid (PF) pathway The correlation analysis was conducted using Pearson’s correlation coefficient in the R package to calculate the correlation coefficient Mantel’srandPvalue (Mantel’sP) of genes and metabolites in the PF pathway. To identify the re...
Understanding the gene regulation mechanism of heat shock response will provide foundation for molecular breeding in this species. The critical survival temperature for marine species usually varied from body size, development stages and acclimation ways (Byrne, 2010; Dong and Dong, 2008). Generally, ...
Integrated analysis of the transcriptome and metabolome reveals the molecular mechanism regulating cotton boll abscission under low light intensity Ning Zhao, Zhao Geng, Guiyuan Zhao, Jianguang Liu, Zetong An, Hanshuang Zhang, Pengfei Ai & Yongqiang Wang BMC Plant Biology volume 24, Arti...
mitotic cell cycle process, mitotic sister chromatid cohesion, mitotic cell cycle phase transition, negative regulation of catalytic activity, regulation of DNA replication, regulation of interleukin-6 production, osteoclast differentiation, regulation of lymphocyte migration, and cellular iron ion homeostasis...
The role of ABA in cold tolerance and seed germination has been well-documented by numerous genetic and physiological studies70,71,72,73,74,75. To explore the molecular mechanism by which OsUBC12 regulates LTG, we first analyzed the expression kinetics of OsUBC12 in response to cold and ABA...
et al. The mechanism of membrane-associated steps in tail-anchored protein insertion. Nature 477, 61–66 (2011). CAS PubMed PubMed Central Google Scholar Wang, F., Chan, C., Weir, N. R. & Denic, V. The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein ...