transcriptionhumantfsfactorsbindingcincinnati LeadingEdgeReviewTheHumanTranscriptionFactorsSamuelA.Lambert,1,9ArttuJolma,2,9LauraF.Campitelli,1,9PratyushK.Das,3YimengYin,4MihaiAlbu,2XiaotingChen,5JussiTaipale,3,4,6,*TimothyR.Hughes,1,2,*andMatthewT.Weirauch5,7,8,*1DepartmentofMolecularGenetics,Universi...
The human protein Zhangfei (ZF) is a member of the bZIP family of transcription factors and was identified through its association with Host Cell Factor (HCF). The mode of action of ZF in the mammalian cell, along with its biological functions, is presently unclear. This thesis is an ...
The human general transcription factor TFIIA is one of several factors involved in specific transcription by RNA polymerase II, possibly by regulating the activity of the TATA-binding subunit (TBP) of TFIID. TFIIA purified from HeLa extracts consists of 35-, 19-, and 12-kDa subunits. Here we...
In order to delineate functional domains that control TNF gene transcription, we have analyzed a 5' flanking region of the human TNF promoter spanning base pairs -115 to -98. This region contains a PEA3/Ets-1 binding motif 5' GAGGA 3' in direct juxtaposition to an AP-1/ATF-like ...
4. Fulton DL, Sundararajan S, Badis G, Hughes TR, Wasserman WW, Roach JC, Sladek R: TFCat: The Curated Catalog of Mouse and Human Transcription Factors. Genome Biol 2009, 10:R29. 5. Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM: A census of human transcription factors: ...
A. et al. The human transcription factors. Cell 172, 650–665 (2018). Article CAS PubMed Google Scholar Kulakovskiy, I. V. et al. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res. 44, D116–D125 (2016). Article CAS...
Forkhead box H1 (FoxH1) is an essential maternal pioneer factor during embryonic development that binds to specific GG/GT-containing DNA target sequences. Here we have determined high-resolution structures of three FoxH1 proteins (from human, frog and fish species) and four DNAs to clarify the...
nouncopy,record,note,summary,notes,version,carbon,log,translation,manuscript,reproduction,duplicate,transcription,carbon copy,transliteration,written versionThey wouldn't let me have a transcript of the interview. Collins Thesaurus of the English Language – Complete and Unabridged 2nd Edition. 2002 © ...
Classification of transcription factors The classification of TFs into 'groups', 'families' and 'subfamilies' is a very important feature of TFe. Over the past few years, there have been efforts to identify and classify all TFs within the human and mouse genomes [4, 5]. While there are po...
A stress pathway master regulator transcription factor, ATF3 is known to share DNA-binding sites with p53, with which it interacts cooperatively13. Moreover, ATF3 overexpression has been implicated in the acceleration of apoptosis in human HepG2 cells14. Western blot analysis revealed a moderate ...