文档标签: transcription factors human motif lovmar motifs 系统标签: transcription factors human motif lovmar motifs CorrectionTheHumanTranscriptionFactorsSamuelA.Lambert,ArttuJolma,LauraF.Campitelli,PratyushK.Das,YimengYin,MihaiAlbu,XiaotingChen,JussiTaipale,*TimothyR.Hughes,*andMatthewT.Weirauch**Corresponde...
数据库, 事实型TRANSPATH is an information system on gene-regulatory pathways, and an extension module to the TRANSFAC database system (Wingender et al., Nucleic Acids Res., 28, 316-319, 2000). It focuses on path...
Importantly, these reports elaborate on important limitations of using GEMMs such as patient specific mutations within transcription factors that are poorly correlated to human disease3,52,53,54. In MAFB KO mice, β-cell formation is merely delayed while α-cells are severely compromised, with no ...
The extraordinary success of mRNA vaccines against coronavirus disease 2019 (COVID-19) has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical trials of mRNA therapeutics include studies of paracrine vascular endothelia
Expression of transcription factors snail, slug, and twist in human bladder carcinoma. J Exp Clin Cancer Res. 2010;29(1):119. Article CAS PubMed PubMed Central Google Scholar Shin NR, Jeong EH, Choi CI, Moon HJ, Kwon CH, Chu IS, et al. Overexpression of snail is associated with ...
AI transcription: Transcription is moving in the AI-only direction at whip speed. Every app I tested has automated transcription available—it's fast, easy, and convenient. Human transcription is great as an add-on feature—especially for industries with plenty of technical jargon—but I didn't...
The clinical response rate to immune checkpoint blockade (ICB) therapy in melanoma remains low, despite its widespread use. Circular non-coding RNAs (circRNAs) are known to play a crucial role in cancer progression and may be a key factor limiting the ef
A direct relationship between these two was reported, as Snai1 targets miR-145 promoter and represses its transcription, while overexpression of miR-145 downregulated this transcription factor. miR-145 was also shown to target important stem cell factors such as KLF4, c-Myc, Nanog, or OCT4. ...
Moreover, Akt can negatively regulate transcription factors, such as NF-κB or FOXO, and increase the production of antiapoptotic and prosurvival genes [43,45,48]. In addition to the inhibition of apoptosis, Akt also regulates cell survival through p27, GSK3, or the mTOR complex. To ...
A notable decrease in anthocyanins accumulation in Yunyan 87 mutant tobacco was attributed to the coordinated downregulation of anthocyanin biosynthetic genes including CHI, F3H, DFR, UFGT, as well as several genes encoding MYB and bHLH transcription factors [38]. Thirteen anthocyanin biosynthetic-...