senescenceTelomerestumorsuppressorgenesAlmost half a century after the first reports describing the limited replicative potential of primary cells in culture, there is now overwhelming evidence for the existence of "cellular senescence" in vivo. It is being recognized as a critical feature of mammalian ...
The essence of senescence Mankind's quest for prevention of aging did not begin or end with the alchemist's search for the magic elixir of life, or Ponce de Leon's voyage to the fou... N Listed - 《Jama》 被引量: 187发表: 1967年 The essence of cellular senescence and how to recogn...
CellEvent Senescence Green can also be used for the detection of cellular senescence in fixed cells for imaging applications. This reagent provides a fluorescent alternative to colorimetric X-gal staining that is the gold standard for detection of senescent cells in imaging, along with the added ben...
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This leads to doxorubicin-induced senescence bypass, activation of the EMT process, increase in the ability of cell migration and invasion, and consequently the induction of an EMT-associated drug resistance phenotype. Results The miR-106bB25 cluster is upregulated in doxorubicin- resistant cells. ...