Kako K, Ishida N. The role of transcription factors in circadian gene expression. Neurosci Res. 1998; 31 :257–264. doi: 10.1016/S0168-0102(98)00054-6. [ Cross Ref ]Itasaki N , Bel-Vialar S , Krumlauf R . 1999 . ‘Shocking’ developments in chick embryology: electroporation and in...
The set of master transcription factors may contain unique transcription factors called pioneer factors that can open compacted chromatin structures and drive the transcriptional activation of target genes. Therefore, pioneer factors may play a central role in direct cellular reprogramming. However, our ...
The plant shoot apical meristem holds a stem cell niche from which all aerial organs originate. Using a computational approach we show that a mixture of monomers and heterodimers of the transcription factors WUSCHEL and HAIRY MERISTEM is sufficient to pa
Inferring the regulatory role of TFs as inducer or repressor if the model is consistent with expression profiles. 4. Isolating ambiguous pieces of information if it is not. The Results section is organised as follows. We first introduce the mathematical framework which is used to define and to ...
13. A dual role of TTF-1 expression in lung adenocarcinoma has been reported14. The mechanisms which control tissue-specific expression of TTF-1, tumor differentiation, and their prognostic significance are not fully understood. One study showed the possible mechanism of suppression of lung ...
Importantly, the infiltration of the interferon-stimulated B-cell subtype and the presence of TLSs correlated with a more favorable prognosis in MIBC. Conclusions The study revealed the heterogeneity of B-cell subtypes in MIBC and suggests a pivotal role of TLSs in MIBC outcomes. Our study ...
The transition from fertilized egg to embryo in chicken requires activation of hundreds of genes that were mostly inactivated before fertilization, which is accompanied with various biological processes. Undoubtedly, transcription factors (TFs) play impo
Here we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration. Our consortium of over 100 researchers has collectively contributed over 130 mini review...
Here, we have demonstrated an essential role for the transcription factor GATA-3, a previously recognized Th2 cell master regulator, in controlling Treg cell function. Treg cell-specific GATA-3 deletion led to a spontaneous inflammatory disorder in mice. GATA-3-null Treg cells were defective in...
Modular nature of Blimp-1 in the regulation of gene expression during B cell maturation. J. Immunol. 172, 5427–5440 (2004). Article CAS PubMed Google Scholar Kwon, K. et al. Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development...