The DEAD-box protein family of RNA helicases. Gene 367, 17–37 (2006). CAS PubMed Google Scholar Jarmoskaite, I. & Russell, R. DEAD-box proteins as RNA helicases and chaperones. Wiley Interdiscip.Rev. RNA 2, 135–152 (2011). CAS PubMed PubMed Central Google Scholar Abdelhaleem,...
The DEAD-box protein family of RNA helicases 2006, Gene Citation Excerpt : It is therefore probable that variants of the Q motif exist in other helicase families. However, whereas it is strictly essential for various DEAD-box proteins in vivo, the role of the glutamine is not vital in seve...
RNA helicases of the DEAD-box protein family all have nine characteristic motifs. These motifs clearly distinguish this family from other, highly related, RNA helicase families such as the DEAH-box or the Ski2 families.The motifs are contained within a core domain that is flanked by less-...
RNA helicases of the DEAD-box protein family all have nine characteristic motifs. These motifs clearly distinguish this family from other, highly related, RNA helicase families such as the DEAH-box or the Ski2 families. The motifs are contained within a core domain that is flanked by less-co...
3.1. Several DEAD-box RNA helicases function in let-7-mediated gene regulation To identify additional components of the miRNA pathway, we knocked down the 37 DEAD-box and 11 DEAH-box helicase genes in C. elegans through RNAi by feeding in an eri-1(mg366); let-7(mg279) background (se...
The protein family of RNA helicases. Crit Rev Biochem Mol Biol. 1998;33(4):259–96. Article CAS PubMed Google Scholar Schwer B. A new twist on RNA helicases: DExH/D box proteins as RNPases. Nat Struct Biol. 2001;8(2):113–6. Article CAS PubMed Google Scholar Tanner NK, ...
p68 (Ddx5) and p72 (Ddx17) are highly related members of the DEAD box family and are established RNA helicases. They have been implicated in growth regulation and have been shown to be involved in both pre-mRNA and pre-rRNA processing. More recently, however, these proteins have been rep...
In the last processing step, the miRNA duplex is assembled with the Argonaute 2 protein to form a ribonucleoprotein complex known as RNA-induced silencing complex (RISC). During RISC assembly, one of the strands in the miRNA duplex is eliminated to render a single-stranded mature miRNA, which...
proteinLAF-1,aDDX3RNAhelicasefoundinPgranules,phase separatesintoPgranule-likedropletsinvitro.Weadaptamicro- rheologytechniquetopreciselymeasuretheviscoelasticityofmi- crometer-sizedLAF-1droplets,revealingpurelyviscousproperties highlytunablebysaltandRNAconcentration.RNAdecreasesvis- ...
p68 (Ddx5) and p72 (Ddx17) are highly related members of the DEAD box family and are established RNA helicases. They have been implicated in growth regulation and have been shown to be involved in both pre-mRNA and pre-rRNA processing. More recently, however, these proteins have been rep...