针对这一科学问题,近期中山大学施松涛教授等研究者在Cell Metabolism杂志上发表的一篇题为“Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation”的文章,该研究提出细胞凋亡是机体硫化氢稳态的重要来源,同时提出干细胞外囊泡...
Figure 1. Th17 Cell Differentiation in Mouse and Man (A) In mouse, naive T cells activated in the presence of TGF-β (possibly provided by Treg cells) and IL-6 begin differentiation toward the Th17 cell subset; IL-6 upregulates IL-21 and IL-23R to further their Th17 development. In ...
CD4+辅助性T淋巴细胞是细胞免疫的介质,在活化其他免疫细胞(如B细胞和细胞毒性T细胞)以及调节免疫反应中起着关键作用。CD4+辅助性T细胞进一步分化为以细胞因子分泌和效应功能为特征的亚群,这些亚群在外周由固有免疫细胞的诱导而实现分化[1]。首先...
These data suggest that IL-17 production is the default program for T-cell differentiation in the absence of DPP2. Thus, DPP2 seems to impose a threshold for quiescent T cells, preventing them from drifting into cell cycle. 展开 关键词: Cell cycle Cell differentiation Cellular proliferation ...
2023年12月18日，中山大学施松涛、中国科学院生物物理研究所陈畅等人在 Cell 子刊 Cell Metabolism 上发表了题为：Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation 的研究论文【1】。该研究揭示了细胞凋亡在维持H2S稳态中的一个之前未知的作用，发现了凋亡细胞产生的凋亡囊泡（apoV）继承了H2S...
4. Role of PI3K/Akt and mTOR complexes in Th17 cell differentiation [C] . Shigenori Nagai, Yutaka Kurebayashi, Shigeo Koyasu Inositol Phospholipid Signaling in Physiology and Disease (Conference) . 2013 机译:PI3K / AKT和MTOR复合物在Th17细胞分化中的作用 5. Characterization of peptides and...
TNF α Promotes Th17 Cell Differentiation through IL-6 and IL-1 β Produced by Monocytes in Rheumatoid Arthritis[J] . Yingxia Zheng,Lei Sun,Ting Jiang... Y Zheng,L Sun,T Jiang,... - 《Journal of Immunology Research》 被引量: 31发表: 2014年 TNFα promotes Th17 cell differentiation throu...
产品名称: Mouse Th17 Cell Differentiation Kit 货号: BR46107 规格: 24T 价格: 1200 品牌: BioRadars 说明书: 下载 产品简介: 首页|公司产品| 公司资讯|联系我们| 版权所有 2017-2020 北京佰瑞达生物科技有限公司 电话/传真:010-69360446 电子邮件:bioradars@yahoo.com 北京市丰台区方庄芳群园二区6号楼6...
Mesenchymal Stem Cells Inhibit Human Th17 Cell Differentiation and Function and Induce a T Regulatory Cell Phenotype Mesenchymal stem cells (MSCs) exert immunomodulatory properties via the inhibition of T cell activation and proliferation. Because of the deleterious role ... S Ghannam,J Pène,G Torcy...