转化生长因子-β(Transforming growth factor beta,TGF-β)是一多功能蛋白质,可以影响多种细胞的生长,分化、细胞凋亡及免疫调节等功能,转化生长因子-β包括三个亚型,转化生长因子-β1,转化生长因子-β2和…
TGF beta-SMAD signal transduction: molecular specificity andfunctional flexibility [J]. Nat Rev Mol Cell Biol, 2007, 8(12): 970 -982. [16] Pinkas J, Teicher B A. Role of TGF-β in Tumor Progression and Metastasis [M]. Cancer Drug Resistance. Humana Press, 2006: 469-489. [17] Do...
20、74.13 DennlerS,GoumansMJ,TenDP.TransforminggrowthfactorbetasignaltransductionJ.JLeukocBiol,2002,71(5):731-740.14 JiF,FuSJ,ShenSL,etal.TheprognosticvalueofcombinedTGF-31andELFinhepatocellularcarcinomaJ.BmcCancer,2015,15(1):116.15 SchmiererB,HillCS.TGFbeta-SMADsignaltransduction:molecularspecificityan...
Regarding the canonical TGFβ pathway, active TGFβ initially binds to the low-affinity accessory TGFβ type III receptor (TβRIII), also named betaglycan, which is abundant on the surface of many cell types (Fig.3a). Betaglycan can present TGFβ to the TGFβ receptor complex, which is ...
[1]. Tojo M, et al.The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 2005 Nov;96(11):791-800. [2]. Chen WP, et al. Pharmacological inhibition of TGFβ receptor improves Nkx2.5 cardiomyoblast-media...
Signals from TGF-beta superfamily receptors are transduced to the nucleus by Smad proteins, which transcriptionally activate target genes. In Caenorhabditi... GI Patterson,A Koweek,A Wong,... - 《Genes Dev》 被引量: 437发表: 1997年 Regulation of a hitchhiking behavior by neuronal insulin and...
英文名称:Recombinant Transforming Growth Factor Beta Receptor I (TGFbR1) 分子式:电询 纯度:99 % 产地:进口/国产 品牌:钰博生物 包装规格:50ug 别名:电询 转化生长因子β受体Ⅰ(TGFβR1)重组蛋白 FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
Recombinant Transforming Growth Factor Beta Receptor I (TGFbR1) FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES! Organism speciesHomo sapiens (Human) Product No.KL397Hu01 SourceProkaryotic expression HostE.coli ...
靶点(Target) TβRI;TβRII CAS号(CAS NO.) 700874-71-1 分子式(Formula) C26H27N5O2 分子量(Molecular Weight) 441.52 外观(Appearance) 粉末 纯度(Purity) ≥98% 溶解性(Solubility) 溶于DMSO:≥22.1 mg/mL 结构式(Structure) 运输和保存方法 ...
Haberstroh, U.et al. TGF-β stimulates rat mesangial cell proliferation in culture: role of PDGF beta-receptor expression.Am. J. Physiol.264, F199–F205 (1993). CASPubMedGoogle Scholar Wilson, H. M.et al. Effect of transforming growth factor-beta 1 on plasminogen activators and plasminogen...