A stem-loop structure immediately following the UGA is needed for selenocysteine incorporation in formate dehydrogenase. Thirteen of the bacterial genomes had homologues of the formate dehydrogenase with the TGA codon at the same site. However, stem-loop structures were much weaker following those TGA...
Apicomplexan parasites have evolved efficient and distinctive strategies for intracellular replication where the timing of emergence of the daughter cells (budding) is a decisive element. However, the molecular mechanisms that provide the proper timing o
The pETmcs vector is a derivative of the vector pET3b with further restriction enzyme sites (KpnI, SnaBI, and HindIII) added to the multiple cloning site downstream of the ATG start codon. This cloning strategy added three amino acids to the N termini of TGA2.1 and TGA2.2. These ...
stop-codonmutationACRS-PCRgrowth traitscattleAs a transcriptional regulatory gene of the SIX family, SIX6 (also known as OPTX2 , SIX9 ), probably affects pituitary development and secretion of hormones, suggesting that this gene is a potential candidate gene for studying association ...
stop-codonmutationACRS-PCRgrowth traitscattleAs a transcriptional regulatory gene of theSIXfamily,SIX6(also known asOPTX2,SIX9), probably affects pituitary development and secretion of hormones, suggesting that this gene is a potential candidate gene for studying association with growth trait in ...
Both htgA and yaaW were inactivated strand specifically by introducing a stop codon. Both mutants exhibited differential phenotypes in biofilm formation and metabolite levels in a nontargeted analysis, suggesting that both are functional despite YaaW but not HtgA could be expressed. While yaaW is ...
We have found an example of the nonsense -thalassemia mutation at codon-37 (TGG TGA) in 3 cases of a Turkish family giving rise to a stop codon. The family studied is originated from eastern region of Turkey. A 37 year-old female patient (case 1) was admitted to our hospital with ...
We describe in a BSS patient the first case of homozygous four bases deletion (TGAG) in the gpIbalpha gene coding sequence, leading to a premature stop codon. In the propositus, blood smears revealed giant platelets (30 x 10(9) platelets/L), and platelet agglutination to ristocetin was ...
BaysalDepartmentF.DepartmentKutlarDepartmentG.DepartmentP.DepartmentWileyBritish Journal of HaematologyRibeiro MLS, Baysal E, Kutlar F, Tamagnini GP, Goncalves P, Lopes D, Huisman THJ (1992) A novel β°-thalassemia mutation (codon 15, TGG→TGA) is prevalent in a population of central Portugal. ...