TF binding sites in subtelomeric regions and nucleosome-free regions.Mirko, FrancesconiRob, JelierBen, Lehner
We trained and tested a logistic regression model, called LR-DNase, to predict binding sites for a specific TF using seven features derived from DNase-seq and genomic sequence. We calculated the area under the precision-recall curve at a false discovery rate cutoff of 0.5 for the LR-DNase ...
CENTIPEDE learns a DNaseI footprint of a transcription factor and predicts its binding sites JF Degner,R Piqueregi 被引量: 0发表: 0年研究点推荐 probabilistic model binding sites 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在...
Transcription factor binding sites often contain several subtypes of sequences that follow not just one but several different patterns. We developed a novel sensitive method based on kernel estimations that is able to reveal subtypes of TF binding sites. The developed method produces patterns in form...
Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Conserved noncoding elements (CNEs) constitute the majority of sequences under purifying selection in the human genome, yet their function remains largely ... Xiaohui,Xie,Mi...
Discover transcription factor (TF) binding specificities/sites (TFBS) using binding site motif sequence and structural information. - akshayparopkari/discover_tfbs
Number of operons, genes and binding sites regulated per TF (RegulonDB 8.5.)doi:10.1371/JOURNAL.PONE.0114347.G002M. RydenfeltHernan G. GarciaR. CoxR. PhillipsPLOS ONE
Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein that inhibits factor VIIa and Xa in the coagulation cascade. It has been shown that forkhead box P3 protein is a TFPI transcriptional repressor. However, there are no studies on chromatin
Near the end of the first repeat is a very basic sequence, and the region surrounding this structure includes separate binding sites for TBP and the acidic activation domain of herpes simplex virus VP16(15, 16). In the absence of other factors, the N- and C-terminal regions of TFIIB ...
Following recent FDA clearance of the Investigational New Drug (IND) application, the trial has expanded to up to 25 sites across the United States. Top-line results are anticipated in 2025. Gastroparesis is a serious and often underdiagnosed disorder characterized by ...