TF binding sites in subtelomeric regions and nucleosome-free regions.Mirko, FrancesconiRob, JelierBen, Lehner
This pattern is the result of the protection provided by CTCF, preferred cross-linking sites, and MNase digestion preference. While further analysis may shed light on specific features of CTCF binding to DNA, it is clear that fragment ends tightly cluster around the CTCF binding consensus, ...
In many cases, true TFBSs are excluded from the identification process, especially when they correspond to low-affinity but important binding sites of regulatory systems. We developed a computational protocol based on molecular and structural criteria to perform biologically meaningful and accurate ...
Number of operons, genes and binding sites regulated per TF (RegulonDB 8.5.)doi:10.1371/JOURNAL.PONE.0114347.G002M. RydenfeltHernan G. GarciaR. CoxR. PhillipsPLOS ONE
Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein that inhibits factor VIIa and Xa in the coagulation cascade. It has been shown that forkhead box P3 protein is a TFPI transcriptional repressor. However, there are no studies on chromatin
Researchers Submit Patent Application, 'Illumination Devices For Sites And Chairs', for Approval (USPTO 20230332761) News editors obtained the following quote from the background information supplied by the inventors:"Flashlights and similar illumination devices are commo... - 《Electronics Newsweekly》...
CENTIPEDE a probabilistic model for learning DNaseI footprints and predicting TF binding sitesNRSFcuts
We developed a novel sensitive method based on kernel estimations that is able to reveal subtypes of TF binding sites. The developed method produces patterns in form of positional weight matrices for the individual subtypes and has been tested on simulated data and compared with several other ...
The goal of most programs developed to find transcription factor binding sites (TFBSs) is the identification of discrete sequence motifs that are significantly over-represented in a given set of sequences where a transcription factor (TF) is expected to bind. These programs assume that the nucleot...
The identification of the preferred DNA binding sites, and their shapes, for all DNA binding proteins will provide an unprecedented and extremely valuable database for anyone attempting to decipher noncoding regulatory DNA. Specifically, we showed that using structural criteria such as the width of ...