直接检测细胞毒性T细胞 聚研是MBL的授权代理 细胞毒性T细胞(cytotoxic T cell,CTL),也称杀伤性T细胞,能特异性杀伤带抗原的靶细胞,如移植细胞、肿瘤细胞及受微生物感染的细胞等。 活化的细胞毒性T细胞分泌功能性细胞因子,如IL-2、干扰素γ(IFNγ)、肿瘤...
MHC tetramers are used for the detection and monitoring of antigen-specific T cells to study the adaptive immune response, including T cell development, disease progression, and evaluation of therapeutics, vaccinations, and other interventions that may have an impact on cellular immune responses. In...
ProT2® MHC Class II Tetramers may be used to study CD4+ T cell immune responses in infectious diseases such as CMV (see figure 1 above) and HCV, and in vaccine studies. ProT2® staining for CD4+ T cell epitopes from HCV
文章标题: Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma 发表期刊:Immunity /2021-07 样本入组:HCC患者外周血,癌旁组织、肿瘤组织 文章结果:1)肝细胞癌(HCC)浸润T细胞的抗原特异性及其与肿瘤控制的相关性;2)CyTOF&...
pMHC tetramerLinking antigen specificity to T cell receptor (TCR) sequences is critical, albeit challenging, to both understanding T cell biology and developing T cell-based therapeutics. Here, we describe in detail tetramer-associated TCR sequencing (TetTCR-Seq), a novel approach to tackling thi...
可以特异性检测抗原特异性T细胞T-SelectMHCTetramer.PDF,可以特异性检测抗原特异性T细胞 T-Select MHC Tetramer 在 T 细胞上表达的 T 细胞受体(T Cell Receptor,TCR)可以特异性识别MHC 分子与肽片段的复合 T-Select MHC Tetramer 物(MHC/peptide complex)并与其结合。1
Reagent for direct detection of antigen-specific T cells. MHC tetramer technology is based on the ability of MHC-peptide complexes to recognize the antigen-specific T cells at a single cell level.
The ability to identify T cells that recognize specific peptide antigens bound to major histocompatibility complex (MHC) molecules has enabled enumeration and molecular characterization of the lymphocytes responsible for cell-mediated immunity. Fluoropho
In nature T cell receptors (TCR) recognize peptide antigens bound to membrane MHC molecules. Quantitative molecular analysis of cell-cell interactions is intrinsically difficult, but MHC glycoproteins are integral membrane molecules that lose their function when dissociated from membranes. Complexes of ...
What are tetramers used for? Tetramers are used to detect specific diseases or infections in the body. Tetramer analysis allows for the detection of specific T-cells. The detection of T-cells helps to identify the presence of disease or infection. ...