经流式细胞水平验证,ACROBiosystems 自主开发的HLA-A*02:01&B2M&NY-ESO-1Tetramer产品,可很好的与TCR结合,且活性明显高于竞品 2e5 of NY-ESO-1 TCR-HEK293 cells (pool) were stained with PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) tetramer Protein(Fig B)and negative control protei...
经流式细胞水平验证,ACROBiosystems 自主开发的HLA-A*02:01&B2M&NY-ESO-1Tetramer产品,可很好的与TCR结合,且活性明显高于竞品 2e5 of NY-ESO-1 TCR-HEK293 cells (pool) were stained with PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) tetramer Pr...
经流式细胞水平验证,ACROBiosystems 自主开发的HLA-A*02:01&B2M&NY-ESO-1 Tetramer产品,可很好的与TCR结合,且活性明显高于竞品 2e5 of NY-ESO-1 TCR-HEK293 cells (pool) were stained with PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) tetramer Protein(Fig B)and negative control prot...
This protein exists in cells as tetramers. 20.研究人员正在探索用tetramer四聚体作为药物传递的载体。 Researchers are exploring the use of tetramers as carriers for drug delivery. 21.这个疾病与tetramer四聚体的异常形成有关。 This disease is associated with abnormal formation of tetramers.©...
CD4+ T cellsepitope specificmagnetic‐bead enrichmentnaive CD4+ T cellsEpitope﹕pecific CD4+ T cells can be labeled in complex cell mixtures from secondary lymphoid organs with fluorophore﹍abeled peptide:major histocompatibility complex class II (p:MHCII) tetramers and then detected by flow ...
Tetramers for CD4+T cells and natural killer T cells exist but have yet to make the same impact as MHC class I tetramers. However, tetramers of non-classical MHC class I molecules (for example, HLA-E) have been important in identifying new pathways of natural-killer-cell regulation. ...
MHC四聚体检测技术是在单细胞水平上标记目标T细胞,并通过流式细胞术对细胞进行分析,从而成为一种快速、简便的检测抗原特异性T细胞(antigen-specificT cells)的定性及定量分析方法。 TCR与MHC-多肽复合物 MHC分子在免疫应答过程中发挥着抗原识别的作用,主要功能是将抗原呈递给T细胞,以区分自身(我们的细胞和组织)和非己...
presents 1 clone and only MFI of bead with tetramer specificity is depicted. E, Percentage of sorted HLA-specific B cells from total memory B cells. F, Percentage of HLA antibody-producing B cell clones from sorted B cells. On the x-axis are the specificity of the tetramers used depicted...
Tetrameric peptide–MHC-class-I complexes (tetramers) allow antigen-specific T cells to be tracked in time and space, as well as a detailed analysis of their surface phenotype. Tetramers are best used in parallel with functional assays. Very large, focused expansions of T-cell populations ...
Tetramer-visualized gluten-specific CD4+ T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten chal- lenge. United European Gastroenterol. J. 2: 268-278.Christophersen A, Raki M, Bergseng E, et al. Tetramer-visualized gluten-specific CD4+ T cells in blood...