TDP-43 (TAR DNA binding protein of 43 kDa; gene name TARDBP) is a 414 amino acid (aa) nuclear RNA/DNA binding phosphoprotein that regulates transcription and splicing. TDP-43 is aberrantly expressed in most forms of amylotrophic lateral sclerosis a...
Full Name TAR DNA binding protein Synonyms TARDBP, TDP 43, TDP43, TDP-43, TAR DNA-binding protein 43 Calculated Molecular Weight 43 kDa Observed Molecular Weight 43 kDa GenBank Accession Number BC001487 Gene Symbol TDP-43 Gene ID (NCBI) 23435 RRID AB_2923716 Conjugate Unconjugated Form Liqui...
Full Name TAR DNA binding protein Calculated Molecular Weight 43 kDa Observed Molecular Weight 43 kDa GenBank Accession Number BC001487 Gene Symbol TDP-43 Gene ID (NCBI) 23435 RRID AB_2240312 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification UNIPROT ID Q13148 Storage...
Gene ID23435 Swiss protQ13148 SynonymsALS10; TDP-43; TDP-43/TARDBP Calculated MW45kDa Observed MWRefer to figures Applications ReactivityHuman, Mouse, Rat Tested applicationsWBIHC-PIF/ICCIPChIPChIP-seqRIPFCFC(Intra)ELISAMeDIPNucleotide ArrayDBFACSCoIPCUT&TagmeRIPInhibition ...
Gene Name TARDBP Accession No. Q13148 Alternate Names ALS10; OTTHUMP00000002171; OTTHUMP00000002172; OTTHUMP00000002173; TADBP_HUMAN; TAR DNA binding protein 43; TAR DNA binding protein; TAR DNA-binding protein 43; TARDBP; TDP 43; TDP-43; TDP43; Description DNA and RNA-binding protein which...
Gene ID23435 SwissProtQ13148 SynonymsTDP43 CategoryTranscription Factors BackgroundRNA结合蛋白,参与RNA生物形成和加工的各个步骤。通过两个RNA识别基序RRM1和RRM2,GU优先结合在RNA分子上,这些RNA分子主要定位在长内含子和mRNAs的3'UTR中。反过来,调节许多非编码和蛋白质编码的RNA的剪接,包括涉及神经元存活的蛋白质,以...
Target NameTDP43 Alternative NamesTAR DNA binding protein, TARDBP Accession No.Swiss-Prot:Q13148 Gene ID:23435 UniprotQ13148 Gene ID23435; Concentration1mg/ml FormulationSupplied in PBS containing 0.02% sodium azide. StorageCan be stored at -20˚C, stable for one year. As with all antibodies...
GeneTARDBP Long Gene nameTAR DNA binding protein synonymousstdp-43ALS10 GenBank acession237331 locs1p36.22 Discovery year2000-01-28 publimed identification7745706 RefSeq identityNM 007375 Havana BLAST/blattothum0000002120 位点特异数据库salsod,肌萎缩侧索硬化症在线基因数据库LRGʓ659MeSH Data NameBlotting...
Encoded by theTARDBPgene, TDP-43 is highly conserved across various species [1]. The protein was initially recognized as a transcription repressor (with a size of 43 kD, hence its name), exhibiting affinity for the TAR DNA sequence of human immunodeficiency virus type 1 (HIV-1) [2]. Subs...
MSDS ¥2200/100 μL Cat No.60019-2-Ig 浓度:1067 μg/ml 库存:现货 点击咨询售前客服 点击咨询售后客服 humanWB View Article humanWB,IP,IHC Nat Neurosci TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration. ...