产品名称: TCF1重组蛋白 基因名: PCBD1 Uniprot No.: P61457 别名: 4 alpha hydroxy tetrahydropterin dehydratase; 4-alpha-hydroxy-tetrahydropterin dehydratase; 6 pyruvoyl tetrahydropterin synthase/dimeriz
The mechanisms underlying the heightened protection mediated by central memory CD8+ T (TCM) cells remain unclear. Here we show that the transcription factor Tcf1 was required in resting TCM cells to generate secondary effector CD8+ T cells and to clear p
Innate lymphoid cells (ILCs) play important functions in immunity and tissue homeostasis, but their development is poorly understood. Through the use of single-cell approaches, we examined the transcriptional and functional heterogeneity of ILC progenito
group after NP-CGG protein immunization (p<0.001). We think that there are two reasons for the decrease of frequency of GC B cells. Firstly, TCF-1 and LEF-1 have an important role in B-cell response, the ablation of TCF-1 and LEF-1 in B cells, also induced by Tamoxifen, may...
TCF1-:TCF表达阴性。 1.表观遗传学研究不支持传统认为的机制 Title: Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade Pubication Data: 2016/10/27 Journal: Science 一直以来,我们认为PD-1治疗可以逆转肿瘤免疫抑制微环境,从而使得瘤内的肿瘤反应性T细胞可以恢复功...
免疫原: Partial TCF1 recombinant protein (116-334 aa) 用途: 科研研究 宿主: 小鼠 保质期: 科研研究 应用范围: ICFC 产地: 进口/国产 标记物: PE 包装规格: 25 tests 品牌: 齐源 抗原来源: 小鼠 适应物种: 人 克隆性: 是 标识物: 科研研究 形态: 液体 保存条件: 2-8℃ 用途: 科研...
4. Bertrand, F., Rochotte, J., Colacios, C., Montfort, A., Tilkin-Mariame, A.F., Touriol, C., Rochaix, P., Lajoie-Mazenc, I., Andrieu-Abadie, N., Levade, T., et al. (2015). Blocking tumor necrosis factor a enhances CD8 T-celldependent immunity in experimental melanoma....
The provision of help from T cells to B cells is a critical component of adaptive humoral immunity1,2. During viral infection, the formation of germinal centers (GCs) by antigen-specific B cells requires key signals provided by follicular helper T cells (TFHcells)3, which results in the dev...
最近的进展使 TCF1 成为人们关注的焦点,因为它在调节成熟 T 细胞反应方面具有多功能。 在细胞毒性 T 细胞谱系中,TCF1 是响应病毒或肿瘤抗原而产生的干细胞样CD8+ T 细胞的自我更新以及保持对检查点阻断免疫疗法的增强反应所必需的。在辅助性 T 细胞谱系中,TCF1 对于T 滤泡辅助细胞和T 滤泡调节细胞的分化是必...
结果BA 初诊组和 BA 缓解组的 miR-3162-3p mRNA、TCF1 mRNA 水平均高于 HC 组,且 BA 初诊组高于 BA 缓解组,差异具有统计学意义(P<0.05);BA 初诊组和 BA 缓解组的 β-catenin mRNA 水平均低于HC 组,且 BA 初诊组低于 BA 缓解组,差异具有统计学意义(P<0.05)。重度阻塞组的 miR-3162-3p mRNA、TCF1...