Next-generation multigenome mapper, expanded ORA compression capability, and more Learn more Services Sequencing Services Microarray Services Proactive Instrument Monitoring Instrument Services & Training All Services Illumina Proactive Instrument Performance Service Our instrument performance service helps red...
whole-genome sequencingethicsBACKGROUND: Whole-genome sequencing (WGS) of Mycobacterium tuberculosis allows rapid, accurate inferences about the sources, location and timing of transmission. However, in an era of heightened concern for personal privacy and science distrust, such inferences could result ...
1. Yang T, Gan M, Liu Q, et al. SAM-TB: a whole genome sequencing data analysis website for detection of Mycobacterium tuberculosis drug resistance and transmission.Brief Bioinform. 2022;23(2):bbac030. doi:10.1093/bib/bbac030 ⋅ 合作单位 ⋅ ...
[37]Dong C, Wei P, Jian X, et al. Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies[J]. Hum Mol Genet, 2015, 24(8): 2125-2137. DOI: 10.1093/hmg/ddu733. [38...
et al. Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study. Lancet Infect. Dis. 15, 1193–1202 (2015). 91. Bradley, P. et al. Rapid antibiotic-resistance predictions from genome sequence data for ...
(DA) method, which identifies known mutations related to drug resistance from whole genome sequencing (WGS) data, such as KvarQ [8], CASTB [9], MyKrobe Predictor TB [10], PhyResSE [11], TGS-TB [12], TBProfiler [5], and SAM-TB [13]. These tools rely heavily on the library of...
Whole genome sequencing (WGS) has become a mainstay in biomedical research. The continually decreasing cost of sequencing has resulted in a data deluge that underlines the need for easy-to-use bioinformatics pipelines that can mine meaningful information from WGS data. SNPTB is one such pipeline ...
Whole-genome sequencing and next-generation sequencing data can be used for directing the process of development during the high-dose therapy. It can also be used to detect and understand the process of microevolution within theM. tuberculosislineages [66] or populations [67], and comprehend the ...
Dr. Alexander Pym from the KwaZulu-Natal Research Institute for Global Health outlined the evolution of TB drug resistance in KwaZulu-Natal, South Africa based on whole genome sequencing and dating analysis of isolates [36]. Dr. Pym and colleagues noted that mutations conferring INH and ...
Whole genome sequencing (WGS) is becoming an important part of epidemiological investigations of infectious diseases due to greater resolution and cost reductions compared to traditional typing approaches. Man... Authors: Hollie-Ann Hatherell, Caroline Colijn, Helen R. Stagg, Charlotte Jackson, Joann...