Intratumoral and intracellular microbes may also regulate the metastatic cascade. Whole genome sequencing revealed a similarity of 99.9% betweenF. nucleatumisolates from primary CRC and liver metastasis, indicating likely bacterial migratory characteristics between these tumor sites49. Microbial regulation of ...
Hence, improvements in complete genome sequencing combined with computational biology and cheminformatics suggest an alluring alternative technique to screen drug targets. In the present study, we have emphasized on the computational techniques to screen drug candidates from whole proteome of fungi and ...
M. et al. Whole-genome sequencing reveals a link between beta-lactam resistance and synthetases of the alarmone (p)ppGpp in Staphylococcus aureus. Microb. Drug Resist. 19, 153–159 (2013). CAS PubMed PubMed Central Google Scholar Givens, R. M. et al. Inducible expression, enzymatic ...
ResultsWe used whole-genome sequencing data produced by two PacBio platforms (Sequel II and RS II) and two ONT protocols (Rapid Sequencing and Ligation Sequencing) to compare assemblies of the bacteriaEscherichia coliand the fruit flyDrosophila ananassae. Sequel II assemblies had higher contiguity an...
Genome size The total number of nucleotides (A + T + G + C) was calculated from the whole nucleotide sequence of each chromosome. GC content (%) The relative frequency (percentage) of guanine and cytosine (G + C)/(A + T + G + C) was calculated from...
All blaNDM-carrying contigs from the whole-genome sequencing (WGS) and MinION sequencing analyses were annotated using the online automated PATRIC server (https://www.patricbrc.org/app/Annotation). Contigs with similar genetic contexts were grouped together based on basic local alignment search tool ...
Whole genome sequencing data of native isolates of Bacillus and Trichoderma having potential biocontrol and plant growth promotion activities in rice. Data Brief 2022, 41, 107923. [Google Scholar] [CrossRef] [PubMed] Mulk, S.; Wahab, A.; Yasmin, H.; Mumtaz, S.; El-Serehy, H.A.; ...
coli genome [217]. The integrated plasmid can still initiate the conjugative transfer of the whole chromosome of the resulting “Hfr” strain (high frequency of recombination). This process of transfer is both progressive and oriented, and the order in which chromosomic genes are transferred ...
Whole genome sequencing of eight selected Vibrio strains indicates that resistant bacteria have more active prophages than susceptible bacteria (Fig. 2a). We could not detect a clear-cut pattern between bacterial-resistance phenotypes and the presence of particular phages, which are shared across ...
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