IL-2, regulatory T cells, and tolerance . J Immunol (2004) 172 ( 7 ):3983–8.10.4049/jimmunol.172.7.3983 [ Cross Ref ]Nelson BH. IL-2, regulatory T cells, and tolerance. J Immunol. 2004; 172 :3983–3988. [ PubMed ]Nelson BH. IL-2, regulatory T cells, and tolerance. J ...
包装规格:5×10^5cells/T25瓶 品牌:艾研 产地:国产 是否进口:否 组织来源:动物 是否是肿瘤细胞:否 小鼠T淋巴细胞;CTLL-2相关产品报价更多> 产品标题价格产地公司名称更新日期 小鼠T淋巴细胞CTLL-2¥1800/瓶上海VIP3年上海雅吉生物科技有限公司2025-01-21询价 ...
产品名称:CTLL-2小鼠T淋巴细胞(50ng/ml IL-2) 型号:HTX2006 生长特性:悬浮 组织来源:小鼠T淋巴细胞(50ng/ml IL-2) 培养基:89%无+10%FBS+1%双抗 物种:小鼠 规格:2X10^6 cells 培养温度:37℃ 引种来源:ATCC 传代:1:2~1:4传代,两天左右换液。
CTLL-2小鼠T淋巴细胞是源自C57BL/6的细胞毒性的T淋巴细胞,是具有细胞毒作用的IL-2依赖型的T-细胞株。 T淋巴细胞来源于骨髓的多能干细胞(胚胎期则来源于卵黄囊和肝)。在人体胚胎期和初生期,骨髓中的一部分多能干细胞或前T细胞迁移到胸腺内,在胸腺激素的诱导下分化成熟,成为具有免疫活性的T细胞。 CTLL-2小鼠T...
1.The immunometabolite S-2-hydroxyglutarate regulates CD8+T-lymphocytefate.Nature.2016 2.Safety and activity of PD-1 blockade-activated DC-CIK cells in patients with advanced solid tumors.OncoImmunology.2018 声明:本文仅作健康科普,不能替代医院的检查和治疗。如有相关疾病,请及时去正规医疗机构就诊,...
One possible mechanism is its direct effects on the neoplastic T cells. To know whether any stage of the diseases can respond to PUVA therapy, we established IL-2 dependent (Sez(+)) and independent cell lines (Sez(-)) originated from a ATL patient with erythroderma and examined in vitro ...
upregulation of inhibitory receptors and downregulation of cytokine and effector-molecule production, thereby rendering T cells dysfunctional in the tumor microenvironment. This molecular pathway is not only present in mouse tumor models but is also observed in people with cancer, identifying IL-2 as ...
IL-2 Is Essential for TGF-β to Convert Naive CD4+CD25 Cells to CD25+Foxp3+ Regulatory T Cells and for Expansion of These Cells IL-2 and TGF-beta both have important roles in the induction and maintenance of immunologic tolerance, but whether these cytokines act separately or togeth... ...
(nuclear factor of activated T cells,NFAT)最初在活化 T 细胞核提取物中被 发现,是一种转录激活因子,可结合白细胞介素 -2 (interleukin-2,IL-2)启动子激活 T 细胞[1].后来 发现 NFAT 广泛表达于多种哺乳动物免疫细胞与组 织细胞,是具有转录活性,多向调节功能的转录因 子[2].近年来,研究发现 NFAT 与...
We show that PD-1 + IL-2 combination therapy, in contrast to PD-1 monotherapy, substantially changes the differentiation program of the PD-1+TCF1+ stem-like CD8+ T cells and results in the generation of transcriptionally and epigenetically distinct effector CD8+ T cells that resemble highly ...