答案是:阶梯设计(the stepped-wedge design) 阶梯设计多用于整群随机试验,评价“利大于弊”的干预措施,尤其在健康教育、免疫接种、筛检、医护人员培训等领域使用较多。这种设计通常不设置专门的对照组,随着试验的进行,各个组都会按照随机结果先后接受这种干预措施。这样就...
Stepped wedge trials may be either individually or cluster-randomized. The stepped wedge design is particularly useful when it is not feasible to provide the intervention to everyone or every community at once, and for evaluating the effectiveness of interventions that have been shown to be ...
A similarly powered cluster randomised controlled trial would require 42 schools.#Stepped wedge trials are a viable design for evaluating school-based physical activity interventions. Incomplete designs, where not all schools are measured at each point, offer the flexibility to work around practical ...
The stepped wedge trial design: a systematic review Background Stepped wedge randomised trial designs involve sequential roll-out of an intervention to participants (individuals or clusters) over a number of... CA Brown,RJ Lilford - 《Bmc Medical Research Methodology》 被引量: 1123发表: 2006年 ...
(Brown & Lilford, 2006) ⇒Celia A Brown, andRichard J Lilford. (2006). “The Stepped Wedge Trial Design: A Systematic Review.” BioMed Central Ltd.doi:10.1186/1471-2288-6-54 Subject Headings:Stepped Wedge Trial Notes Cited By
In this article, we present a typology to characterise the full range of stepped wedge designs, and offer guidance on several other design aspects. We developed a framework to define and report the key characteristics of a stepped wedge trial, including cluster allocation and individual ...
The First International Conference on the Stepped Wedge Trial Design was hosted by the York Trials Unit, Department of Health Sciences, University of York on 10 March 2016. The conference brought together national and international delegates with experience, expertise or interest in this design which...
This makes the stepped wedge design particularly useful for evaluating the population-level impact of an intervention that has been shown to be effective in an individually randomized trial. The unidirectional aspect of the crossover does, however, complicate the analysis since the treatment effect ...
Stepped Wedge Design A form of Cluster randomized controlled trial in which the intervention is administered in a random sequence to all clusters over time, so that all clusters will have received the intervention at the end of the trial. Each time point at which a new cluster receives the ...
The stepped wedge trial design: a systematic review. BMC Med Res Methodol. 2006;6:54. Article PubMed PubMed Central Google Scholar Esri. What is GIS? http://www.esri.com/what-is-gis. Accessed 13 Feb 2015. The College of Physicians and Surgeons of Ontario. All doctors search. http:/...