The stepped wedge research design is becoming increasingly popular, particularly in the field of implementation science. It is a form of cluster randomised controlled trial with unidirectional cross-over (normally from control to intervention). This trial design may be biased however because the effect...
The stepped wedge research design is becoming increasingly popular, particularly in the field of implementation science. It is a form of cluster randomised controlled trial with unidirectional cross-over (normally from control to intervention). This trial design may be biased however because the effect...
This motivating example provides a context for the theoretical and simulation results shown in Section 3 where we describe statistical aspects of the design and analysis of stepped wedge CRTs. In Section 4 we summarize our findings and discuss future areas of research....
Tele-Kasper is a stepped-wedge cluster-randomized trial that will be conducted across non-university children’s hospitals in Germany. The intervention consists of a telemedical consultation service in the form of a network in different German areas, using an app as a communication tool. The ...
The stepped-wedge (SW) cluster randomized controlled trial, in which clusters cross over in a randomized sequence from control to intervention, is ideal for the implementation and testing of complex health service interventions. In certain cases however, implementation of the intervention may pose logi...
The stepped wedge design does not inherently have more power than a cluster randomized controlled trial. ., Arts, I., Crutzen, R., Viechtbauer, W.: The stepped wedge design does not inherently have more power than a cluster randomized controlled trial... D Kotz,M Spigt,ICW Arts,... -...
All articles, conference abstracts, protocols and trial registrations of original randomised research studies that used or planned to use a stepped wedge design, from any field of research, were eligible. We excluded studies retrospectively analysed as a stepped wedge design when the study was not ...
The systematic review of Eichner, Groenwold [57] shows concerns about reaching the sample size with the stepped wedge design. However, we assume that the advantages outweigh these considerations. To counteract the threat of not reaching a sufficiently large sample size, we made careful arrangements...
Design and analysis of stepped wedge cluster randomized trials[J]. Contemporary Clinical Trials, 2007, 28(2): 182 – 191. DOI: 10.1016/j.cct.2006.05.007 [6] Brown CA, Lilford RJ. The stepped wedge trial design: a systematic review[J]. BMC Medical Research Methodology, 2006, 6: 54....
Study design The overall study uses a stepped-wedge design, as shown in Fig.1. This design lends itself to implementation science research adaptation and mixed methods [31]. It also has several logistical and scientific advantages, as it involves incremental execution of the intervention; allows ...