Stepped Wedge Designsdesign effectsample size calculationstepped wedge designtest interventionOne type of cluster trial is that in which the clusters are maintained over successive periods of time during which, for example, all will commence on the standard intervention for the condition concerned and,...
答案是:阶梯设计(the stepped-wedge design) 阶梯设计多用于整群随机试验,评价“利大于弊”的干预措施,尤其在健康教育、免疫接种、筛检、医护人员培训等领域使用较多。这种设计通常不设置专门的对照组,随着试验的进行,各个组都会按照随机结果先后接受这种干预措施。这样就...
Stepped wedge trials may be either individually or cluster-randomized. The stepped wedge design is particularly useful when it is not feasible to provide the intervention to everyone or every community at once, and for evaluating the effectiveness of interventions that have been shown to be ...
In Section 2 we describe a trial being conducted in Washington state that uses a stepped wedge design. This motivating example provides a context for the theoretical and simulation results shown in Section 3 where we describe statistical aspects of the design and analysis of stepped wedge CRTs. ...
The analysis of data from such a design involves the comparison of the intervention “wedge” (i.e., data from the clusters that have received the intervention during a step) with the control wedge... ... Access to the complete content on Oxford Reference requires a subscription or purchas...
We sought to optimise the design of stepped wedge trials with an equal allocation of clusters to sequences and explored sample size comparisons with alternative trial designs. We developed a new expression for the design effect for a stepped wedge trial, assuming that observations are equally correl...
This is an example of a study-within-a-trial with a closed cohort stepped wedge design whereby all sites begin in the control state and the monthly recruitment rate is measured until after all sites have been allocated to the intervention. Acknowledgements The PRIME trial is funded by the Br...
As a motivating example, we consider the stepped wedge trial on expedited partner therapy (EPT) in Washington state summarized by Golden et al [5]. With EPT, when an individual tests positive for a sexually transmitted infection, their sex partners are then offered treatment without medical evalu...
Service evaluation of a pilot to improve primary care sexual health services in England implemented using a stepped wedge design 来自 onAcademic 喜欢 0 阅读量: 21 作者:K Town,EJ Ricketts,CAM Mcnulty,T Hartney,A Nardone,N Ockendon,KA Folkard,A Charlett,JK Dunbar ...
Stepped-Wedge Design Overview eFigure 2. Example Clinician Emails by Performance eFigure 3. Serious Illness Conversations for High-Risk Patients by Clinic eTable 1. High-Risk Patient Encounter Characteristics eTable 2. Patient Encounters and SIC Rates by Clinic and Control vs Intervention eTable 3...