Mesenchymal stem cells, for instance, contain proteins, mRNAs, and miRNAs that can alter the function and fate of the recipient cells.* Because of their ability to transport a variety of material to target cells, exosomes have been the subject of many medical therapies (exosomal therapy)....
ExosomesRegenerative medicineCell therapyOver the past decades, stem cells derived from amnion (amniotic epithelial cells and amniotic mesenchymal stem cells) have gained growing attention in regenerative medicine and emerged as a novel and alternative source for cell therapy. Several proof-of-principle ...
In this review, the applications of stem cells and exosomes for the NEC therapy are investigated. Our review principally aims to integrate current studies on NEC therapy by stem cells and exosomes and therefore provides insights for the development and application of novel therapeutic strategies for ...
Exosomes are extracellular vesicles secreted by cells to help deliver chemical messages to other cells in the body. Exosomes, like MSCs, hold promise as a clinical intervention for multiple diseases and health conditions. Due to the ubiquitous nature (nearly all cells secrete exosomes) and unique p...
Methods: Exosomes were isolated from the conditioned medium of bone marrow-derived mesenchymal stem cells using ultrafiltration and size-exclusion chromatography and were identified by nanoparticle tracking analysis and immunoblottin...
(MSCs), but whether exosomes derived from MSCs suppress or promote angiogenesis remain paradoxical. The purpose of this study focused on understanding the potential role of exosomes derived from stem cells of human deciduous...
间充质干细胞(Mesenchymal stem cells, MSC)具有独特的自我更新、多向分化、免疫调节和旁分泌的功能。MSC分泌的外泌体(Exosomes)被认为是细胞间通信的中心媒介,具有较高的归巢效率和较低的致瘤风险,因此在许多疾病治疗中显示出良好的治疗潜力。研究表明不同组织来源的MSC具有异质性,但是其分泌的外泌体是否存在功能差...
第二篇,论著文章“The combination of G-CSF and AMD3100 mobilizes bone marrow-derived stem cells to protect against cisplatin-induced acute kidney injury in mice”,于2021年1月21号投稿,2021年3月4号接收,用时一个多月。 第三篇,综述文章“Mesenchymal stromal/stem cells and their exosomes for restora...
Joint-preserving regenerative therapies involving core decompression (CD), enhanced with cells, growth factors, and bone substitutes, have been developed but lack extensive validation. Exosomes are emerging as a promising regenerative therapy. Human adipose stem cell (hADSC)-derived exosomes exhibit ...
Diabetes and its complications place a heavy financial strain on both patients and the global healthcare establishment. The lack of effective treatments contributes to this pessimistic situation and negative outlook. Exosomes released from mesenchymal stromal cells (MSCs) have emerged as the most likely...