Stem cell therapy may provide a biological treatment alternative to traditional pharmacological therapy. Mesenchymal stem cells (MSCs) are preferred because of their differentiation ability and possible derivation from many adult tissues. In addition, the paracrine effects of MSCs play crucial anti-...
Mesenchymal stem cell-derived exosomes (MSCs-Exos) have demonstrated comparable efficacy to MSCs in the treatment of diabetes and its associated complications [8]. MSCs-Exos have shown a superior therapeutic and regenerative effect in treating DM compared with the original cells in some research ...
This review provides an overview of recent developments in our understanding of exosomes secreted by mesenchymal stem cells (MSCs) and cardiac cells over the past five years. Certain exosomes exhibit great potential in the treatment of MI, while others impact the progression and prognosis of MI [6...
Stem cells such as bone marrow mesenchymal stem cells (BMSCs) and adipose mesenchymal stem cells (AMSCs) have shown potent cartilage regeneration ability and have been clinically tested for OA treatment.158,159,160 Clinical trials of intra-articular injection of MSCs into the knee with OA have ...
No treatment can reverse the progress of OA. Since exosomes were first reported in 1983, researches have been conducted to explore the mechanisms and therapeutic potential of exosomes in treating OA. Exosomes derived from Mesenchymal stem cells have attracted increasingly attention in tackling disease....
However, to date, few reports have demonstrated the use of exosomes derived from human pluripotent stem cells for the treatment of skin aging. In this study, we collected exosomes from the conditioned medium of human induced pluripotent stem cells (iPSCs) and investigated the effect on aged ...
However, it seems that the greater challenge is finding a treatment that will address a combination of the core autistic behaviors, including social–communicational and repetitive/restricted interests. In our previous study, we have shown that intraventricular administration of mesenchymal stem cells (...
study mesenchymal stem cells (mscs) with regenerative and differentiation capabilities have received much attention among ophthalmologists and scientists as an alternative modality in thetreatment of corneal diseases. recently, a research...
Prolonged healing and scar formation are two major challenges in the treatment of soft tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue regeneration, and recent studies have suggested that exosomes se... H Li,J Wang,Z Xin,... - 《Sci Rep》 被引量: ...
Mesenchymal stem cells (MSCs) are a component of the tumor microenvironment and can promote the development of gastric cancer through paracrine mechanism. However, the effects of MSCexosomes (MSCex) on gastric cancer are less clear. The present study reported that MSCex promoted the proliferative ...